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Titin isoform switching is a major cardiac adaptive response in hibernating grizzly bears

The hibernation phenomenon captures biological as well as clinical interests to understand how organs adapt. Here we studied how hibernating grizzly bears (Ursus arctos horribilis) tolerate extremely low heart rates without developing cardiac chamber dilation. We evaluated cardiac filling function i...

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Detalhes bibliográficos
Main Authors: Nelson, O. Lynne, Robbins, Charles T., Wu, Yiming, Granzier, Henk
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2494771/
https://ncbi.nlm.nih.gov/pubmed/18502907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00234.2008
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