Positioning Metabolism as a Central Player in the Diabetic Heart

Autor Mereweather, Laura J., Montes Aparicio, Claudia N., Heather, Lisa C.
Vydáno v J Lipid Atheroscler (2020)

In vivo assessment of pyruvate dehydrogenase flux in the heart using hyperpolarized carbon-13 magnetic resonance

Autor Schroeder, Marie A., Cochlin, Lowri E., Heather, Lisa C., Clarke, Kieran, Radda, George K., Tyler, Damian J.
Vydáno 2008

Changes in Cardiac Substrate Transporters and Metabolic Proteins Mirror the Metabolic Shift in Patients with Aortic Stenosis

Autor Heather, Lisa C., Howell, Neil J., Emmanuel, Yaso, Cole, Mark A., Frenneaux, Michael P., Pagano, Domenico, Clarke, Kieran
Vydáno 2011

Determining In Vivo Regulation of Cardiac Pyruvate Dehydrogenase Based on Label Flux from Hyperpolarized [1-(13)C]Pyruvate

Autor Schroeder, Marie A., Atherton, Helen J., Heather, Lisa C., Griffin, Julian L., Clarke, Kieran, Radda, George K., Tyler, Damian J.
Vydáno v NMR Biomed (2011)

Simultaneous in vivo assessment of cardiac and hepatic metabolism in the diabetic rat using hyperpolarized MRS

Autor Le Page, Lydia M., Ball, Daniel R., Ball, Vicky, Dodd, Michael S., Miller, Jack J., Heather, Lisa C., Tyler, Damian J.
Vydáno v NMR Biomed (2016)

Cardiac metabolism in a new rat model of type 2 diabetes using high-fat diet with low dose streptozotocin

Autor Mansor, Latt S, Gonzalez, Eileen R, Cole, Mark A, Tyler, Damian J, Beeson, Jessica H, Clarke, Kieran, Carr, Carolyn A, Heather, Lisa C
Vydáno 2013

The Role of PDH Inhibition in the Development of Hypertrophy in the Hyperthyroid Rat Heart: A Combined MRI and Hyperpolarized MRS Study

Autor Atherton, Helen J., Dodd, Michael S., Heather, Lisa C., Schroeder, Marie A., Griffin, Julian L., Radda, George K., Clarke, Kieran, Tyler, Damian J.
Vydáno v Circulation (2011)

The von Hippel-Lindau Chuvash mutation in mice alters cardiac substrate and high-energy phosphate metabolism

Autor Slingo, Mary, Cole, Mark, Carr, Carolyn, Curtis, Mary K., Dodd, Michael, Giles, Lucia, Heather, Lisa C., Tyler, Damian, Clarke, Kieran, Robbins, Peter A.
Vydáno v Am J Physiol Heart Circ Physiol (2016)

Rescue of myocardial energetic dysfunction in diabetes through the correction of mitochondrial hyperacetylation by honokiol

Autor Kerr, Matthew, Miller, Jack J., Thapa, Dharendra, Stiewe, Sophie, Timm, Kerstin N., Aparicio, Claudia N. Montes, Scott, Iain, Tyler, Damian J., Heather, Lisa C.
Vydáno v JCI Insight (2020)

Increasing Pyruvate Dehydrogenase Flux as a Treatment for Diabetic Cardiomyopathy: A Combined (13)C Hyperpolarized Magnetic Resonance and Echocardiography Study

Autor Le Page, Lydia M., Rider, Oliver J., Lewis, Andrew J., Ball, Vicky, Clarke, Kieran, Johansson, Edvin, Carr, Carolyn A., Heather, Lisa C., Tyler, Damian J.
Vydáno v Diabetes (2015)

Real-time assessment of Krebs cycle metabolism using hyperpolarized (13)C magnetic resonance spectroscopy

Autor Schroeder, Marie A., Atherton, Helen J., Ball, Daniel R., Cole, Mark A., Heather, Lisa C., Griffin, Julian L., Clarke, Kieran, Radda, George K., Tyler, Damian J.
Vydáno 2009

A high fat diet increases mitochondrial fatty acid oxidation and uncoupling to decrease efficiency in rat heart

Autor Cole, Mark A., Murray, Andrew J., Cochlin, Lowri E., Heather, Lisa C., McAleese, Sara, Knight, Nicholas S., Sutton, Elizabeth, Jamil, Amira Abd, Parassol, Nadege, Clarke, Kieran
Vydáno 2011

Dietary nitrate increases arginine availability and protects mitochondrial complex I and energetics in the hypoxic rat heart

Autor Ashmore, Tom, Fernandez, Bernadette O, Branco-Price, Cristina, West, James A, Cowburn, Andrew S, Heather, Lisa C, Griffin, Julian L, Johnson, Randall S, Feelisch, Martin, Murray, Andrew J
Vydáno v J Physiol (2014)

Dimethyl-2-oxoglutarate improves redox balance and mitochondrial function in muscle pericytes of individuals with diabetes mellitus

Autor Faulkner, Ashton, Tamiato, Anita, Cathery, William, Rampin, Andrea, Caravaggi, Carlo Maria, Jover, Eva, Allen, Steve, Mellor, Harry, Hauton, David, Heather, Lisa C., Spinetti, Gaia, Madeddu, Paolo
Vydáno v Diabetologia (2020)

L-Carnitine Stimulates In Vivo Carbohydrate Metabolism in the Type 1 Diabetic Heart as Demonstrated by Hyperpolarized MRI

Autor Savic, Dragana, Ball, Vicky, Curtis, M. Kate, Sousa Fialho, Maria da Luz, Timm, Kerstin N., Hauton, David, West, James, Griffin, Julian, Heather, Lisa C., Tyler, Damian J.
Vydáno v Metabolites (2021)

Impaired In Vivo Mitochondrial Krebs Cycle Activity After Myocardial Infarction Assessed Using Hyperpolarized Magnetic Resonance Spectroscopy

Autor Dodd, Michael S., Atherton, Helen J., Carr, Carolyn A., Stuckey, Daniel J., West, James A., Griffin, Julian L., Radda, George K., Clarke, Kieran, Heather, Lisa C., Tyler, Damian J.
Vydáno v Circ Cardiovasc Imaging (2014)

Validation of the In Vivo Assessment of Pyruvate Dehydrogenase Activity Using Hyperpolarized (13)C-Magnetic Resonance Spectroscopy

Autor Atherton, Helen J., Schroeder, Marie A., Dodd, Michael S., Heather, Lisa C., Carter, Emma E., Cochlin, Lowri E., Nagel, Simon, Sibson, Nicola R., Radda, George K., Clarke, Kieran, Tyler, Damian J.
Vydáno v NMR Biomed (2010)

In Vivo Alterations in Cardiac Metabolism and Function in the Spontaneously Hypertensive Rat Heart

Autor Dodd, Michael S., Ball, Daniel R., Schroeder, Marie A., Le Page, Lydia M., Atherton, Helen J., Heather, Lisa C., Seymour, Anne-Marie, Ashrafian, Houman, Watkins, Hugh, Clarke, Kieran, Tyler, Damian J.
Vydáno v Cardiovasc Res (2012)

Assessing the effect of hypoxia on cardiac metabolism using hyperpolarized (13)C magnetic resonance spectroscopy

Autor Le Page, Lydia M., Rider, Oliver J., Lewis, Andrew J., Noden, Victoria, Kerr, Matthew, Giles, Lucia, Ambrose, Lucy J.A., Ball, Vicky, Mansor, Latt, Heather, Lisa C., Tyler, Damian J.
Vydáno v NMR Biomed (2019)

Rapid, [Formula: see text] ‐insensitive, dual‐band quasi‐adiabatic saturation transfer with optimal control for complete quantification of myocardial ATP flux

Autor Miller, Jack J., Valkovič, Ladislav, Kerr, Matthew, Timm, Kerstin N., Watson, William D., Lau, Justin Y. C., Tyler, Andrew, Rodgers, Christopher, Bottomley, Paul A., Heather, Lisa C., Tyler, Damian J.
Vydáno v Magn Reson Med (2021)