Evaluation of a target region capture sequencing platform using monogenic diabetes as a study-model

par Gao, Rui, Liu, Yanxia, Gjesing, Anette Prior, Hollensted, Mette, Wan, Xianzi, He, Shuwen, Pedersen, Oluf, Yi, Xin, Wang, Jun, Hansen, Torben
Publié 2014

Potential mechanism of enhanced postprandial glucagon‐like peptide‐1 release following treatment with a diacylglycerol acyltransferase 1 inhibitor

par Liu, Jinqi, McLaren, David G., Chen, Dunlu, Kan, Yanqing, Stout, Steven J., Shen, Xiaolan, Murphy, Beth Ann, Forrest, Gail, Karanam, Bindhu, Sonatore, Lisa, He, Shuwen, Roddy, Thomas P., Pinto, Shirly
Publié dans Pharmacol Res Perspect (2015)

Identification and Characterization of Sebaceous Gland Atrophy-Sparing DGAT1 Inhibitors

par Muise, Eric S., Zhu, Yonghua, Verras, Andreas, Karanam, Bindhu V., Gorski, Judith, Weingarth, Drew, Lin, Hua V., Hwa, Joyce, Thompson, John R., Hu, Guanghui, Liu, Jian, He, Shuwen, DeVita, Robert J., Shen, Dong-Ming, Pinto, Shirly
Publié 2014

Stimulation of Glucose-Dependent Insulin Secretion by a Potent, Selective sst(3) Antagonist

par Pasternak, Alexander, Feng, Zhe, de Jesus, Reynalda, Ye, Zhixiong, He, Shuwen, Dobbelaar, Peter, Bradley, Scott A., Chicchi, Gary G., Tsao, Kwei-Lan, Trusca, Dorina, Eiermann, George J., Li, Cai, Feng, Yue, Wu, Margaret, Shao, Qing, Zhang, Bei B., Nargund, Ravi, Mills, Sander G., Howard, Andrew D., Yang, Lihu, Zhou, Yun-Ping
Publié 2012

Diamine Derivatives as Novel Small-Molecule, Potent, and Subtype-Selective Somatostatin SST3 Receptor Agonists

par Li, Derun, Wu, Zhicai, Yu, Yang, Ball, Richard G., Guo, Liangqin, Sherer, Edward, He, Shuwen, Hong, Qingmei, Lai, Zhong, Qi, Hongbo, Truong, Quang, Yang, David X., Chicchi, Gary G., Tsao, Kwei-Lan, Trusca, Dorina, Trujillo, Maria, Pachanski, Michele, Eiermann, George J., Howard, Andrew D., Zhou, Yun-Ping, Zhang, Bei B., Nargund, Ravi P., Hagmann, William K.
Publié 2014

Potent DGAT1 Inhibitors in the Benzimidazole Class with a Pyridyl-oxy-cyclohexanecarboxylic Acid Moiety

par He, Shuwen, Hong, Qingmei, Lai, Zhong, Wu, Zhicai, Yu, Yang, Kim, David W., Ting, Pauline C., Kuethe, Jeffrey T., Yang, Ginger X., Jian, Tianying, Liu, Jian, Guiadeen, Deodial, Krikorian, Arto D., Sperbeck, Donald M., Sonatore, Lisa M., Wiltsie, Judyann, Chung, Christine C., Gibson, Jack T., Lisnock, JeanMarie, Murphy, Beth A., Gorski, Judith N., Liu, Jinqi, Chen, Dunlu, Chen, Xiaoli, Wolff, Michael, Tong, Sharon X., Madeira, Maria, Karanam, Bindhu V., Shen, Dong-Ming, Balkovec, James M., Pinto, Shirly, Nargund, Ravi P., DeVita, Robert J.
Publié 2013

Discovery of a Potent and Selective DGAT1 Inhibitor with a Piperidinyl-oxy-cyclohexanecarboxylic Acid Moiety

par He, Shuwen, Hong, Qingmei, Lai, Zhong, Yang, David X., Ting, Pauline C., Kuethe, Jeffrey T., Cernak, Timothy A., Dykstra, Kevin D., Sperbeck, Donald M., Wu, Zhicai, Yu, Yang, Yang, Ginger X., Jian, Tianying, Liu, Jian, Guiadeen, Deodial, Krikorian, Arto D., Sonatore, Lisa M., Wiltsie, Judyann, Liu, Jinqi, Gorski, Judith N., Chung, Christine C., Gibson, Jack T., Lisnock, JeanMarie, Xiao, Jianying, Wolff, Michael, Tong, Sharon X., Madeira, Maria, Karanam, Bindhu V., Shen, Dong-Ming, Balkovec, James M., Pinto, Shirly, Nargund, Ravi P., DeVita, Robert J.
Publié 2014

Investigation of Cardiovascular Effects of Tetrahydro-β-carboline sstr3 antagonists

par He, Shuwen, Lai, Zhong, Ye, Zhixiong, Dobbelaar, Peter H., Shah, Shrenik K., Truong, Quang, Du, Wu, Guo, Liangqin, Liu, Jian, Jian, Tianying, Qi, Hongbo, Bakshi, Raman K., Hong, Qingmei, Dellureficio, James, Reibarkh, Mikhail, Samuel, Koppara, Reddy, Vijay B., Mitelman, Stan, Tong, Sharon X., Chicchi, Gary G., Tsao, Kwei-Lan, Trusca, Dorina, Wu, Margaret, Shao, Qing, Trujillo, Maria E., Fernandez, Guillermo, Nelson, Donald, Bunting, Patricia, Kerr, Janet, Fitzgerald, Patrick, Morissette, Pierre, Volksdorf, Sylvia, Eiermann, George J., Li, Cai, Zhang, Bei, Howard, Andrew D., Zhou, Yun-Ping, Nargund, Ravi P., Hagmann, William K.
Publié 2014

The Discovery of MK-4256, a Potent SSTR3 Antagonist as a Potential Treatment of Type 2 Diabetes

par He, Shuwen, Ye, Zhixiong, Truong, Quang, Shah, Shrenik, Du, Wu, Guo, Liangqin, Dobbelaar, Peter H., Lai, Zhong, Liu, Jian, Jian, Tianying, Qi, Hongbo, Bakshi, Raman K., Hong, Qingmei, Dellureficio, James, Pasternak, Alexander, Feng, Zhe, deJesus, Reynalda, Yang, Lihu, Reibarkh, Mikhail, Bradley, Scott A., Holmes, Mark A., Ball, Richard G., Ruck, Rebecca T., Huffman, Mark A., Wong, Frederick, Samuel, Koppara, Reddy, Vijay B., Mitelman, Stan, Tong, Sharon X., Chicchi, Gary G., Tsao, Kwei-Lan, Trusca, Dorina, Wu, Margaret, Shao, Qing, Trujillo, Maria E., Eiermann, George J., Li, Cai, Zhang, Bei B., Howard, Andrew D., Zhou, Yun-Ping, Nargund, Ravi P., Hagmann, William K.
Publié 2012

Discovery of MK-1421, a Potent, Selective sstr3 Antagonist, as a Development Candidate for Type 2 Diabetes

par Shah, Shrenik K., He, Shuwen, Guo, Liangqin, Truong, Quang, Qi, Hongbo, Du, Wu, Lai, Zhong, Liu, Jian, Jian, Tianying, Hong, Qingmei, Dobbelaar, Peter, Ye, Zhixiong, Sherer, Edward, Feng, Zhe, Yu, Yang, Wong, Frederick, Samuel, Koppara, Madiera, Maria, Karanam, Bindhu V., Reddy, Vijay B., Mitelman, Stan, Tong, Sharon X., Chicchi, Gary G., Tsao, Kwei-Lan, Trusca, Dorina, Feng, Yue, Wu, Margaret, Shao, Qing, Trujillo, Maria E., Eiermann, George J., Li, Cai, Pachanski, Michele, Fernandez, Guillermo, Nelson, Donald, Bunting, Patricia, Morissette, Pierre, Volksdorf, Sylvia, Kerr, Janet, Zhang, Bei B., Howard, Andrew D., Zhou, Yun-Ping, Pasternak, Alexander, Nargund, Ravi P., Hagmann, William K.
Publié dans ACS Med Chem Lett (2015)