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Diamine Derivatives as Novel Small-Molecule, Potent, and Subtype-Selective Somatostatin SST3 Receptor Agonists
[Image: see text] A novel class of small-molecule, highly potent, and subtype-selective somatostatin SST3 agonists was discovered through modification of a SST3 antagonist. As an example, (1R,2S)-9 demonstrated not only potent in vitro SST3 agonist activity but also in vivo SST3 agonist activity in...
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Autors principals: | , , , , , , , , , , , , , , , , , , , , , , |
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Format: | Artigo |
Idioma: | Inglês |
Publicat: |
American Chemical
Society
2014
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Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4060944/ https://ncbi.nlm.nih.gov/pubmed/24944745 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml500079u |
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