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Structural insights into the activation of somatostatin receptor 2 by cyclic SST analogues

Abstract The endogenous cyclic tetradecapeptide SST14 was reported to stimulate all five somatostatin receptors (SSTR1–5) for hormone release, neurotransmission, cell growth arrest and cancer suppression. Two SST14-derived short cyclic SST analogues (lanreotide or octreotide) with improved stability...

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Detalhes bibliográficos
Main Authors: Qing Bo, Fan Yang, Yingge Li, Xianyu Meng, Huanhuan Zhang, Yingxin Zhou, Shenglong Ling, Demeng Sun, Pei Lv, Lei Liu, Pan Shi, Changlin Tian
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2022-05-01
Colecção:Cell Discovery
Acesso em linha:https://doi.org/10.1038/s41421-022-00405-2
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