Evaluation of a target region capture sequencing platform using monogenic diabetes as a study-model

Tekijä Gao, Rui, Liu, Yanxia, Gjesing, Anette Prior, Hollensted, Mette, Wan, Xianzi, He, Shuwen, Pedersen, Oluf, Yi, Xin, Wang, Jun, Hansen, Torben
Julkaistu 2014

Potential mechanism of enhanced postprandial glucagon‐like peptide‐1 release following treatment with a diacylglycerol acyltransferase 1 inhibitor

Tekijä Liu, Jinqi, McLaren, David G., Chen, Dunlu, Kan, Yanqing, Stout, Steven J., Shen, Xiaolan, Murphy, Beth Ann, Forrest, Gail, Karanam, Bindhu, Sonatore, Lisa, He, Shuwen, Roddy, Thomas P., Pinto, Shirly
Julkaisussa Pharmacol Res Perspect (2015)

Identification and Characterization of Sebaceous Gland Atrophy-Sparing DGAT1 Inhibitors

Tekijä Muise, Eric S., Zhu, Yonghua, Verras, Andreas, Karanam, Bindhu V., Gorski, Judith, Weingarth, Drew, Lin, Hua V., Hwa, Joyce, Thompson, John R., Hu, Guanghui, Liu, Jian, He, Shuwen, DeVita, Robert J., Shen, Dong-Ming, Pinto, Shirly
Julkaistu 2014

Stimulation of Glucose-Dependent Insulin Secretion by a Potent, Selective sst(3) Antagonist

Tekijä Pasternak, Alexander, Feng, Zhe, de Jesus, Reynalda, Ye, Zhixiong, He, Shuwen, Dobbelaar, Peter, Bradley, Scott A., Chicchi, Gary G., Tsao, Kwei-Lan, Trusca, Dorina, Eiermann, George J., Li, Cai, Feng, Yue, Wu, Margaret, Shao, Qing, Zhang, Bei B., Nargund, Ravi, Mills, Sander G., Howard, Andrew D., Yang, Lihu, Zhou, Yun-Ping
Julkaistu 2012

Diamine Derivatives as Novel Small-Molecule, Potent, and Subtype-Selective Somatostatin SST3 Receptor Agonists

Tekijä Li, Derun, Wu, Zhicai, Yu, Yang, Ball, Richard G., Guo, Liangqin, Sherer, Edward, He, Shuwen, Hong, Qingmei, Lai, Zhong, Qi, Hongbo, Truong, Quang, Yang, David X., Chicchi, Gary G., Tsao, Kwei-Lan, Trusca, Dorina, Trujillo, Maria, Pachanski, Michele, Eiermann, George J., Howard, Andrew D., Zhou, Yun-Ping, Zhang, Bei B., Nargund, Ravi P., Hagmann, William K.
Julkaistu 2014

Potent DGAT1 Inhibitors in the Benzimidazole Class with a Pyridyl-oxy-cyclohexanecarboxylic Acid Moiety

Tekijä He, Shuwen, Hong, Qingmei, Lai, Zhong, Wu, Zhicai, Yu, Yang, Kim, David W., Ting, Pauline C., Kuethe, Jeffrey T., Yang, Ginger X., Jian, Tianying, Liu, Jian, Guiadeen, Deodial, Krikorian, Arto D., Sperbeck, Donald M., Sonatore, Lisa M., Wiltsie, Judyann, Chung, Christine C., Gibson, Jack T., Lisnock, JeanMarie, Murphy, Beth A., Gorski, Judith N., Liu, Jinqi, Chen, Dunlu, Chen, Xiaoli, Wolff, Michael, Tong, Sharon X., Madeira, Maria, Karanam, Bindhu V., Shen, Dong-Ming, Balkovec, James M., Pinto, Shirly, Nargund, Ravi P., DeVita, Robert J.
Julkaistu 2013

Discovery of a Potent and Selective DGAT1 Inhibitor with a Piperidinyl-oxy-cyclohexanecarboxylic Acid Moiety

Tekijä He, Shuwen, Hong, Qingmei, Lai, Zhong, Yang, David X., Ting, Pauline C., Kuethe, Jeffrey T., Cernak, Timothy A., Dykstra, Kevin D., Sperbeck, Donald M., Wu, Zhicai, Yu, Yang, Yang, Ginger X., Jian, Tianying, Liu, Jian, Guiadeen, Deodial, Krikorian, Arto D., Sonatore, Lisa M., Wiltsie, Judyann, Liu, Jinqi, Gorski, Judith N., Chung, Christine C., Gibson, Jack T., Lisnock, JeanMarie, Xiao, Jianying, Wolff, Michael, Tong, Sharon X., Madeira, Maria, Karanam, Bindhu V., Shen, Dong-Ming, Balkovec, James M., Pinto, Shirly, Nargund, Ravi P., DeVita, Robert J.
Julkaistu 2014

Investigation of Cardiovascular Effects of Tetrahydro-β-carboline sstr3 antagonists

Tekijä He, Shuwen, Lai, Zhong, Ye, Zhixiong, Dobbelaar, Peter H., Shah, Shrenik K., Truong, Quang, Du, Wu, Guo, Liangqin, Liu, Jian, Jian, Tianying, Qi, Hongbo, Bakshi, Raman K., Hong, Qingmei, Dellureficio, James, Reibarkh, Mikhail, Samuel, Koppara, Reddy, Vijay B., Mitelman, Stan, Tong, Sharon X., Chicchi, Gary G., Tsao, Kwei-Lan, Trusca, Dorina, Wu, Margaret, Shao, Qing, Trujillo, Maria E., Fernandez, Guillermo, Nelson, Donald, Bunting, Patricia, Kerr, Janet, Fitzgerald, Patrick, Morissette, Pierre, Volksdorf, Sylvia, Eiermann, George J., Li, Cai, Zhang, Bei, Howard, Andrew D., Zhou, Yun-Ping, Nargund, Ravi P., Hagmann, William K.
Julkaistu 2014

The Discovery of MK-4256, a Potent SSTR3 Antagonist as a Potential Treatment of Type 2 Diabetes

Tekijä He, Shuwen, Ye, Zhixiong, Truong, Quang, Shah, Shrenik, Du, Wu, Guo, Liangqin, Dobbelaar, Peter H., Lai, Zhong, Liu, Jian, Jian, Tianying, Qi, Hongbo, Bakshi, Raman K., Hong, Qingmei, Dellureficio, James, Pasternak, Alexander, Feng, Zhe, deJesus, Reynalda, Yang, Lihu, Reibarkh, Mikhail, Bradley, Scott A., Holmes, Mark A., Ball, Richard G., Ruck, Rebecca T., Huffman, Mark A., Wong, Frederick, Samuel, Koppara, Reddy, Vijay B., Mitelman, Stan, Tong, Sharon X., Chicchi, Gary G., Tsao, Kwei-Lan, Trusca, Dorina, Wu, Margaret, Shao, Qing, Trujillo, Maria E., Eiermann, George J., Li, Cai, Zhang, Bei B., Howard, Andrew D., Zhou, Yun-Ping, Nargund, Ravi P., Hagmann, William K.
Julkaistu 2012

Discovery of MK-1421, a Potent, Selective sstr3 Antagonist, as a Development Candidate for Type 2 Diabetes

Tekijä Shah, Shrenik K., He, Shuwen, Guo, Liangqin, Truong, Quang, Qi, Hongbo, Du, Wu, Lai, Zhong, Liu, Jian, Jian, Tianying, Hong, Qingmei, Dobbelaar, Peter, Ye, Zhixiong, Sherer, Edward, Feng, Zhe, Yu, Yang, Wong, Frederick, Samuel, Koppara, Madiera, Maria, Karanam, Bindhu V., Reddy, Vijay B., Mitelman, Stan, Tong, Sharon X., Chicchi, Gary G., Tsao, Kwei-Lan, Trusca, Dorina, Feng, Yue, Wu, Margaret, Shao, Qing, Trujillo, Maria E., Eiermann, George J., Li, Cai, Pachanski, Michele, Fernandez, Guillermo, Nelson, Donald, Bunting, Patricia, Morissette, Pierre, Volksdorf, Sylvia, Kerr, Janet, Zhang, Bei B., Howard, Andrew D., Zhou, Yun-Ping, Pasternak, Alexander, Nargund, Ravi P., Hagmann, William K.
Julkaisussa ACS Med Chem Lett (2015)