Stromal TGFβR2 signaling: a gateway to progression for pancreatic cancer

Por Hagopian, Moriah M, Brekken, Rolf A
Publicado no Mol Cell Oncol (2014)

Neutralizing murine TGFβR2 promotes a differentiated tumor cell phenotype and inhibits pancreatic cancer metastasis

Por Ostapoff, Katherine T., Cenik, Bercin Kutluk, Wang, Miao, Ye, Risheng, Xu, Xiaohong, Nugent, Desiree, Hagopian, Moriah M., Topalovski, Mary, Rivera, Lee B., Carroll, Kyla D., Brekken, Rolf A.
Publicado em 2014

Inhibition of discoidin domain receptor 1 reduces collagen-mediated tumorigenicity in pancreatic ductal adenocarcinoma

Por Aguilera, Kristina Y., Huang, Huocong, Du, Wenting, Hagopian, Moriah M., Wang, Zhen, Hinz, Stefan, Hwang, Tae Hyun, Wang, Huamin, Fleming, Jason B., Castrillon, Diego H., Ren, Xiaomei, Ding, Ke, Brekken, Rolf A.
Publicado no Mol Cancer Ther (2017)

Targeting TGFβR2‐mutant tumors exposes vulnerabilities to stromal TGFβ blockade in pancreatic cancer

Por Huang, Huocong, Zhang, Yuqing, Gallegos, Valerie, Sorrelle, Noah, Zaid, Mohamed Medhat, Toombs, Jason, Du, Wenting, Wright, Steven, Hagopian, Moriah, Wang, Zhaoning, Hosein, Abdel Nasser, Sathe, Adwait Amod, Xing, Chao, Koay, Eugene J, Driscoll, Kyla E, Brekken, Rolf A
Publicado no EMBO Mol Med (2019)