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Stromal TGFβR2 signaling: a gateway to progression for pancreatic cancer
The function of transforming growth factor β (TGFβ) in the progression of pancreatic ductal adenocarcinoma (PDA) is complex and therapeutic targeting of this pathway is challenging. We showed that antibody-mediated inhibition of stromal Tgfβr2 prevented or reversed epithelial plasticity resulting in...
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| Vydáno v: | Mol Cell Oncol |
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| Hlavní autoři: | , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Taylor & Francis
2014
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4905287/ https://ncbi.nlm.nih.gov/pubmed/27308449 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/23723556.2014.975606 |
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