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Stromal TGFβR2 signaling: a gateway to progression for pancreatic cancer

The function of transforming growth factor β (TGFβ) in the progression of pancreatic ductal adenocarcinoma (PDA) is complex and therapeutic targeting of this pathway is challenging. We showed that antibody-mediated inhibition of stromal Tgfβr2 prevented or reversed epithelial plasticity resulting in...

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Bibliografski detalji
Izdano u:Mol Cell Oncol
Glavni autori: Hagopian, Moriah M, Brekken, Rolf A
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905287/
https://ncbi.nlm.nih.gov/pubmed/27308449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/23723556.2014.975606
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