Stromal TGF-β signaling induces AR activation in prostate cancer

AR signaling is essential for the growth and survival of prostate cancer (PCa), including most of the lethal castration-resistant PCa (CRPC). We previously reported that TGF-β signaling in prostate stroma promotes prostate tumor angiogenesis and growth. By using a PCa/stroma co-culture model, here w...

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Publicat a:Oncotarget
Autors principals: Yang, Feng, Chen, Yizhen, Shen, Tao, Guo, Dan, Dakhova, Olga, Ittmann, Michael M., Creighton, Chad J., Zhang, Yiqun, Dang, Truong D., Rowley, David R.
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2014
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4279415/
https://ncbi.nlm.nih.gov/pubmed/25333263
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