Notch and TGFβ Form a Reciprocal Positive Regulatory Loop that Suppresses Murine Prostate Basal Stem/Progenitor Cell Activity

The role of Notch signaling in the maintenance of adult murine prostate epithelial homeostasis remains unclear. We found that Notch ligands are mainly expressed within the basal cell lineage, while active Notch signaling is detected in both the prostate basal and luminal cell lineages. Disrupting th...

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Bibliografiset tiedot
Päätekijät: Valdez, Joseph M, Zhang, Li, Su, Qingtai, Dakhova, Olga, Zhang, Yiqun, Shahi, Payam, Spencer, David M, Creighton, Chad J, Ittmann, Michael M, Xin, Li
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2012
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3490134/
https://ncbi.nlm.nih.gov/pubmed/23122291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2012.07.003
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