TGF-β and αvβ6 integrin act in a common pathway to suppress pancreatic cancer progression

The TGFβ pathway is under active consideration as a cancer drug target based on its capacity to promote cancer cell invasion and to create a pro-tumorigenic microenvironment. However, the clinical application of TGFβ inhibitors remains uncertain as genetic studies demonstrate a tumor suppressor func...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Hezel, Aram F., Deshpande, Vikram, Zimmerman, Stephanie M., Contino, Gianmarco, Alagesan, Brinda, O’Dell, Michael R., Rivera, Lee B., Harper, Jay, Lonning, Scott, Brekken, Rolf A., Bardeesy, Nabeel
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3764481/
https://ncbi.nlm.nih.gov/pubmed/22787119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-0634
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi