TGFβ-mediated expression of TGFβ-activating integrins in SSc monocytes: disturbed activation of latent TGFβ?

INTRODUCTION: The pathophysiology of systemic sclerosis (SSc) is closely linked to overactive TGFβ signaling. TGFβ is produced and circulates in latent form, making its activation crucial for signaling. This activation can be mediated via integrins. We investigated the balance between active and lat...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Arthritis Res Ther
Main Authors: van Caam, A., Aarts, J., van Ee, T., Vitters, E., Koenders, M., van de Loo, F., van Lent, P., van den Hoogen, F., Thurlings, R., Vonk, M. C., van der Kraan, P. M.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7059334/
https://ncbi.nlm.nih.gov/pubmed/32143707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-020-2130-5
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker