Expression of TGF-β Signaling Regulator RBPMS (RNA-Binding Protein With Multiple Splicing) Is Regulated by IL-1β and TGF-β Superfamily Members, and Decreased in Aged and Osteoarthritic Cartilage

OBJECTIVE: RNA-binding protein with multiple splicing (RBPMS) has been shown to physically interact with Smads and enhance transforming growth factor-β (TGF-β)–mediated Smad2/3 transcriptional activity in mammalian cells. Objective of this study was to examine whether expression of RBPMS is regulate...

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Опубликовано в: :Cartilage
Главные авторы: Shanmugaapriya, S., van Caam, A., de Kroon, L., Vitters, Elly L., Walgreen, B, van Beuningen, H., Davidson, E. Blaney, van der Kraan, Peter M.
Формат: Artigo
Язык:Inglês
Опубликовано: SAGE Publications 2016
Предметы:
Basic Research Papers
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5029562/
https://ncbi.nlm.nih.gov/pubmed/27688842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947603515623991
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