Expression of transforming growth factor‐β (TGFβ) and the TGFβ signalling molecule SMAD‐2P in spontaneous and instability‐induced osteoarthritis: role in cartilage degradation, chondrogenesis and osteophyte formation

BACKGROUND: The primary feature of osteoarthritis is cartilage loss. In addition, osteophytes can frequently be observed. Transforming growth factor‐β (TGFβ) has been suggested to be associated with protection against cartilage damage and new cartilage formation as seen in osteophytes. OBJECTIVE: To...

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Detalhes bibliográficos
Main Authors: Davidson, E N Blaney, Vitters, E L, van der Kraan, P M, van den Berg, W B
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2006
Assuntos:
Extended Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1798346/
https://ncbi.nlm.nih.gov/pubmed/16439443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2005.045971
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