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A role for age-related changes in TGFβ signaling in aberrant chondrocyte differentiation and osteoarthritis

Transforming growth factor beta (TGFβ) is a growth factor with many faces. In our osteoarthritis (OA) research we have found that TGFβ can be protective as well as deleterious for articular cartilage. We postulate that the dual effects of TGFβ on chondrocytes can be explained by the fact that TGFβ c...

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Detaylı Bibliyografya
Asıl Yazarlar: van der Kraan, Peter M, Blaney Davidson, Esmeralda N, van den Berg, Wim B
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2875624/
https://ncbi.nlm.nih.gov/pubmed/20156325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2896
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