SMAD3 and SMAD4 have a more dominant role than SMAD2 in TGFβ-induced chondrogenic differentiation of bone marrow-derived mesenchymal stem cells

To improve cartilage formation by bone marrow-derived mesenchymal stem cells (BMSCs), the signaling mechanism governing chondrogenic differentiation requires better understanding. We previously showed that the transforming growth factor-β (TGFβ) receptor ALK5 is crucial for chondrogenesis induced by...

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Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: de Kroon, Laurie M. G., Narcisi, Roberto, van den Akker, Guus G. H., Vitters, Elly L., Blaney Davidson, Esmeralda N., van Osch, Gerjo J. V. M., van der Kraan, Peter M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2017
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5327413/
https://ncbi.nlm.nih.gov/pubmed/28240243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43164
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