Structural Dynamics of Actin during Active Interaction with Myosin Depends on the Isoform of the Essential Light Chain

por Prochniewicz, Ewa, Guhathakurta, Piyali, Thomas, David D.
Publicado 2013

Amplitude of the actomyosin power stroke depends strongly on the isoform of the myosin essential light chain

por Guhathakurta, Piyali, Prochniewicz, Ewa, Thomas, David D.
Publicado en Proc Natl Acad Sci U S A (2015)

Actin-Myosin Interaction: Structure, Function and Drug Discovery

por Guhathakurta, Piyali, Prochniewicz, Ewa, Thomas, David D.
Publicado en Int J Mol Sci (2018)

A Cardiomyopathy Mutation in the Myosin Essential Light Chain Alters Actomyosin Structure

por Guhathakurta, Piyali, Prochniewicz, Ewa, Roopnarine, Osha, Rohde, John A., Thomas, David D.
Publicado en Biophys J (2017)

Allosteric Communication in Dictyostelium Myosin II

por Guhathakurta, Piyali, Prochniewicz, Ewa, Muretta, Joseph M., Titus, Margaret A., Thomas, David D.
Publicado 2012

High-throughput screen, using time-resolved FRET, yields actin-binding compounds that modulate actin–myosin structure and function

por Guhathakurta, Piyali, Prochniewicz, Ewa, Grant, Benjamin D., Peterson, Kurt C., Thomas, David D.
Publicado en J Biol Chem (2018)

Actin-binding compounds, previously discovered by FRET-based high-throughput screening, differentially affect skeletal and cardiac muscle

por Guhathakurta, Piyali, Phung, Lien A., Prochniewicz, Ewa, Lichtenberger, Sarah, Wilson, Anna, Thomas, David D.
Publicado en J Biol Chem (2020)

Novel drug discovery platform for spinocerebellar ataxia, using fluorescence technology targeting β-III-spectrin

por Rebbeck, Robyn T., Andrick, Anna K., Denha, Sarah A., Svensson, Bengt, Guhathakurta, Piyali, Thomas, David D., Hays, Thomas S., Avery, Adam W.
Publicado en J Biol Chem (2020)

Cardiac myosin-binding protein C interaction with actin is inhibited by compounds identified in a high-throughput fluorescence lifetime screen

por Bunch, Thomas A., Guhathakurta, Piyali, Lepak, Victoria C., Thompson, Andrew R., Kanassatega, Rhye-Samuel, Wilson, Anna, Thomas, David D., Colson, Brett A.
Publicado en J Biol Chem (2021)