Mining Tertiary Structural Motifs for Assessment of Designability

par Zhang, Jian, Grigoryan, Gevorg
Publié dans Methods Enzymol (2013)

Rapid search for tertiary fragments reveals protein sequence–structure relationships

par Zhou, Jianfu, Grigoryan, Gevorg
Publié dans Protein Sci (2015)

Sequence statistics of tertiary structural motifs reflect protein stability

par Zheng, Fan, Grigoryan, Gevorg
Publié dans PLoS One (2017)

Structural specificity in coiled-coil interactions

par Grigoryan, Gevorg, Keating, Amy E.
Publié 2008

Protein Structural Motifs in Prediction and Design

par Mackenzie, Craig O., Grigoryan, Gevorg
Publié dans Curr Opin Struct Biol (2017)

Modest membrane hydrogen bonds deliver rich results

par Grigoryan, Gevorg, DeGrado, William F
Publié 2008

Probing Designability via a Generalized Model of Helical Bundle Geometry

par Grigoryan, Gevorg, DeGrado, William F.
Publié 2010

Contact prediction is hardest for the most informative contacts, but improves with the incorporation of contact potentials

par Holland, Jack, Pan, Qinxin, Grigoryan, Gevorg
Publié dans PLoS One (2018)

Structure-based design of combinatorial mutagenesis libraries

par Verma, Deeptak, Grigoryan, Gevorg, Bailey-Kellogg, Chris
Publié dans Protein Sci (2015)

Tertiary alphabet for the observable protein structural universe

par Mackenzie, Craig O., Zhou, Jianfu, Grigoryan, Gevorg
Publié dans Proc Natl Acad Sci U S A (2016)

A general-purpose protein design framework based on mining sequence–structure relationships in known protein structures

par Zhou, Jianfu, Panaitiu, Alexandra E., Grigoryan, Gevorg
Publié dans Proc Natl Acad Sci U S A (2020)

Pareto optimization of combinatorial mutagenesis libraries

par Verma, Deeptak, Grigoryan, Gevorg, Bailey-Kellogg, Chris
Publié dans IEEE/ACM Trans Comput Biol Bioinform (2018)

Design of protein-interaction specificity affords selective bZIP-binding peptides

par Grigoryan, Gevorg, Reinke, Aaron W., Keating, Amy E.
Publié 2009

Identification of bZIP interaction partners of viral proteins HBZ, MEQ, BZLF1, and K-bZIP using coiled-coil arrays

par Reinke, Aaron W., Grigoryan, Gevorg, Keating, Amy E.
Publié 2010

Transmembrane Communication: General Principles and Lessons from the Structure and Function of the M2 Proton Channel, K(+) Channels, and Integrin Receptors

par Grigoryan, Gevorg, Moore, David T., DeGrado, William F.
Publié 2011

The accommodation index measures the perturbation associated with insertions and deletions in coiled‐coils: Application to understand signaling in histidine kinases

par Schmidt, Nathan W., Grigoryan, Gevorg, DeGrado, William F.
Publié dans Protein Sci (2017)

Design of self-assembling transmembrane helical bundles to elucidate principles required for membrane protein folding and ion transport

par Joh, Nathan H., Grigoryan, Gevorg, Wu, Yibing, DeGrado, William F.
Publié dans Philos Trans R Soc Lond B Biol Sci (2017)

Tertiary structural motif sequence statistics enable facile prediction and design of peptides that bind anti-apoptotic Bfl-1 and Mcl-1

par Frappier, Vincent, Jenson, Justin M., Zhou, Jianfu, Grigoryan, Gevorg, Keating, Amy E.
Publié dans Structure (2019)

Deletion of Na(+)/H(+) exchanger regulatory factor 2 represses colon cancer progress by suppression of Stat3 and CD24

par Yoshida, Michihiro, Zhao, Luqing, Grigoryan, Gevorg, Shim, Hyunsuk, He, Peijian, Yun, C. Chris
Publié dans Am J Physiol Gastrointest Liver Physiol (2016)

Computational Design of Selective Peptides to Discriminate Between Similar PDZ Domains in an Oncogenic Pathway

par Zheng, Fan, Jewell, Heather, Fitzpatrick, Jeremy, Zhang, Jian, Mierke, Dale F., Grigoryan, Gevorg
Publié dans J Mol Biol (2014)