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Computational Design of Selective Peptides to Discriminate Between Similar PDZ Domains in an Oncogenic Pathway
Reagents that target protein-protein interactions to rewire signaling are of great relevance in biological research. Computational protein design may offer a means of creating such reagents on demand, but methods for encoding targeting selectivity are sorely needed. This is especially challenging wh...
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| Publicado no: | J Mol Biol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4970318/ https://ncbi.nlm.nih.gov/pubmed/25451599 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2014.10.014 |
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