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Transmembrane Communication: General Principles and Lessons from the Structure and Function of the M2 Proton Channel, K(+) Channels, and Integrin Receptors

Signal transduction across biological membranes is central to life. This process generally happens through communication between different domains and hierarchical coupling of information. Here, we review structural and thermodynamic principles behind transmembrane (TM) signal transduction and discu...

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Autors principals: Grigoryan, Gevorg, Moore, David T., DeGrado, William F.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3767166/
https://ncbi.nlm.nih.gov/pubmed/21548783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-biochem-091008-152423
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