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Probing Designability via a Generalized Model of Helical Bundle Geometry

Because the space of folded protein structures is highly degenerate, with recurring secondary and tertiary motifs, methods for representing protein structure in terms of collective physically-relevant coordinates are of great interest. By collapsing structural diversity to a handful of parameters, s...

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Détails bibliographiques
Auteurs principaux: Grigoryan, Gevorg, DeGrado, William F.
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3052747/
https://ncbi.nlm.nih.gov/pubmed/20932976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.08.058
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