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Crystal structure of the drug‐resistant S31N influenza M2 proton channel
The M2 protein is a small proton channel found in the influenza A virus that is necessary for viral replication. The M2 channel is the target of a class of drugs called the adamantanes, which block the channel pore and prevent the virus from replicating. In recent decades mutations have arisen in M2...
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Publicado en: | Protein Sci |
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Autores principales: | , |
Formato: | Artigo |
Lenguaje: | Inglês |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4972211/ https://ncbi.nlm.nih.gov/pubmed/27082171 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2937 |
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