Mining Tertiary Structural Motifs for Assessment of Designability

por Zhang, Jian, Grigoryan, Gevorg
Publicado en Methods Enzymol (2013)

Rapid search for tertiary fragments reveals protein sequence–structure relationships

por Zhou, Jianfu, Grigoryan, Gevorg
Publicado en Protein Sci (2015)

Sequence statistics of tertiary structural motifs reflect protein stability

por Zheng, Fan, Grigoryan, Gevorg
Publicado en PLoS One (2017)

Structural specificity in coiled-coil interactions

por Grigoryan, Gevorg, Keating, Amy E.
Publicado 2008

Protein Structural Motifs in Prediction and Design

por Mackenzie, Craig O., Grigoryan, Gevorg
Publicado en Curr Opin Struct Biol (2017)

Modest membrane hydrogen bonds deliver rich results

por Grigoryan, Gevorg, DeGrado, William F
Publicado 2008

Probing Designability via a Generalized Model of Helical Bundle Geometry

por Grigoryan, Gevorg, DeGrado, William F.
Publicado 2010

Contact prediction is hardest for the most informative contacts, but improves with the incorporation of contact potentials

por Holland, Jack, Pan, Qinxin, Grigoryan, Gevorg
Publicado en PLoS One (2018)

Structure-based design of combinatorial mutagenesis libraries

por Verma, Deeptak, Grigoryan, Gevorg, Bailey-Kellogg, Chris
Publicado en Protein Sci (2015)

Tertiary alphabet for the observable protein structural universe

por Mackenzie, Craig O., Zhou, Jianfu, Grigoryan, Gevorg
Publicado en Proc Natl Acad Sci U S A (2016)

A general-purpose protein design framework based on mining sequence–structure relationships in known protein structures

por Zhou, Jianfu, Panaitiu, Alexandra E., Grigoryan, Gevorg
Publicado en Proc Natl Acad Sci U S A (2020)

Pareto optimization of combinatorial mutagenesis libraries

por Verma, Deeptak, Grigoryan, Gevorg, Bailey-Kellogg, Chris
Publicado en IEEE/ACM Trans Comput Biol Bioinform (2018)

Design of protein-interaction specificity affords selective bZIP-binding peptides

por Grigoryan, Gevorg, Reinke, Aaron W., Keating, Amy E.
Publicado 2009

Identification of bZIP interaction partners of viral proteins HBZ, MEQ, BZLF1, and K-bZIP using coiled-coil arrays

por Reinke, Aaron W., Grigoryan, Gevorg, Keating, Amy E.
Publicado 2010

Transmembrane Communication: General Principles and Lessons from the Structure and Function of the M2 Proton Channel, K(+) Channels, and Integrin Receptors

por Grigoryan, Gevorg, Moore, David T., DeGrado, William F.
Publicado 2011

The accommodation index measures the perturbation associated with insertions and deletions in coiled‐coils: Application to understand signaling in histidine kinases

por Schmidt, Nathan W., Grigoryan, Gevorg, DeGrado, William F.
Publicado en Protein Sci (2017)

Design of self-assembling transmembrane helical bundles to elucidate principles required for membrane protein folding and ion transport

por Joh, Nathan H., Grigoryan, Gevorg, Wu, Yibing, DeGrado, William F.
Publicado en Philos Trans R Soc Lond B Biol Sci (2017)

Tertiary structural motif sequence statistics enable facile prediction and design of peptides that bind anti-apoptotic Bfl-1 and Mcl-1

por Frappier, Vincent, Jenson, Justin M., Zhou, Jianfu, Grigoryan, Gevorg, Keating, Amy E.
Publicado en Structure (2019)

Deletion of Na(+)/H(+) exchanger regulatory factor 2 represses colon cancer progress by suppression of Stat3 and CD24

por Yoshida, Michihiro, Zhao, Luqing, Grigoryan, Gevorg, Shim, Hyunsuk, He, Peijian, Yun, C. Chris
Publicado en Am J Physiol Gastrointest Liver Physiol (2016)

Computational Design of Selective Peptides to Discriminate Between Similar PDZ Domains in an Oncogenic Pathway

por Zheng, Fan, Jewell, Heather, Fitzpatrick, Jeremy, Zhang, Jian, Mierke, Dale F., Grigoryan, Gevorg
Publicado en J Mol Biol (2014)