Mining Tertiary Structural Motifs for Assessment of Designability

by Zhang, Jian, Grigoryan, Gevorg
Published in Methods Enzymol (2013)

Rapid search for tertiary fragments reveals protein sequence–structure relationships

by Zhou, Jianfu, Grigoryan, Gevorg
Published in Protein Sci (2015)

Sequence statistics of tertiary structural motifs reflect protein stability

by Zheng, Fan, Grigoryan, Gevorg
Published in PLoS One (2017)

Structural specificity in coiled-coil interactions

by Grigoryan, Gevorg, Keating, Amy E.
Published 2008

Protein Structural Motifs in Prediction and Design

by Mackenzie, Craig O., Grigoryan, Gevorg
Published in Curr Opin Struct Biol (2017)

Modest membrane hydrogen bonds deliver rich results

by Grigoryan, Gevorg, DeGrado, William F
Published 2008

Probing Designability via a Generalized Model of Helical Bundle Geometry

by Grigoryan, Gevorg, DeGrado, William F.
Published 2010

Contact prediction is hardest for the most informative contacts, but improves with the incorporation of contact potentials

by Holland, Jack, Pan, Qinxin, Grigoryan, Gevorg
Published in PLoS One (2018)

Structure-based design of combinatorial mutagenesis libraries

by Verma, Deeptak, Grigoryan, Gevorg, Bailey-Kellogg, Chris
Published in Protein Sci (2015)

Tertiary alphabet for the observable protein structural universe

by Mackenzie, Craig O., Zhou, Jianfu, Grigoryan, Gevorg
Published in Proc Natl Acad Sci U S A (2016)

A general-purpose protein design framework based on mining sequence–structure relationships in known protein structures

by Zhou, Jianfu, Panaitiu, Alexandra E., Grigoryan, Gevorg
Published in Proc Natl Acad Sci U S A (2020)

Pareto optimization of combinatorial mutagenesis libraries

by Verma, Deeptak, Grigoryan, Gevorg, Bailey-Kellogg, Chris
Published in IEEE/ACM Trans Comput Biol Bioinform (2018)

Design of protein-interaction specificity affords selective bZIP-binding peptides

by Grigoryan, Gevorg, Reinke, Aaron W., Keating, Amy E.
Published 2009

Identification of bZIP interaction partners of viral proteins HBZ, MEQ, BZLF1, and K-bZIP using coiled-coil arrays

by Reinke, Aaron W., Grigoryan, Gevorg, Keating, Amy E.
Published 2010

Transmembrane Communication: General Principles and Lessons from the Structure and Function of the M2 Proton Channel, K(+) Channels, and Integrin Receptors

by Grigoryan, Gevorg, Moore, David T., DeGrado, William F.
Published 2011

The accommodation index measures the perturbation associated with insertions and deletions in coiled‐coils: Application to understand signaling in histidine kinases

by Schmidt, Nathan W., Grigoryan, Gevorg, DeGrado, William F.
Published in Protein Sci (2017)

Design of self-assembling transmembrane helical bundles to elucidate principles required for membrane protein folding and ion transport

by Joh, Nathan H., Grigoryan, Gevorg, Wu, Yibing, DeGrado, William F.
Published in Philos Trans R Soc Lond B Biol Sci (2017)

Tertiary structural motif sequence statistics enable facile prediction and design of peptides that bind anti-apoptotic Bfl-1 and Mcl-1

by Frappier, Vincent, Jenson, Justin M., Zhou, Jianfu, Grigoryan, Gevorg, Keating, Amy E.
Published in Structure (2019)

Deletion of Na(+)/H(+) exchanger regulatory factor 2 represses colon cancer progress by suppression of Stat3 and CD24

by Yoshida, Michihiro, Zhao, Luqing, Grigoryan, Gevorg, Shim, Hyunsuk, He, Peijian, Yun, C. Chris
Published in Am J Physiol Gastrointest Liver Physiol (2016)

Computational Design of Selective Peptides to Discriminate Between Similar PDZ Domains in an Oncogenic Pathway

by Zheng, Fan, Jewell, Heather, Fitzpatrick, Jeremy, Zhang, Jian, Mierke, Dale F., Grigoryan, Gevorg
Published in J Mol Biol (2014)