Mining Tertiary Structural Motifs for Assessment of Designability

gan Zhang, Jian, Grigoryan, Gevorg
Cyhoeddwyd yn Methods Enzymol (2013)

Rapid search for tertiary fragments reveals protein sequence–structure relationships

gan Zhou, Jianfu, Grigoryan, Gevorg
Cyhoeddwyd yn Protein Sci (2015)

Sequence statistics of tertiary structural motifs reflect protein stability

gan Zheng, Fan, Grigoryan, Gevorg
Cyhoeddwyd yn PLoS One (2017)

Structural specificity in coiled-coil interactions

gan Grigoryan, Gevorg, Keating, Amy E.
Cyhoeddwyd 2008

Protein Structural Motifs in Prediction and Design

gan Mackenzie, Craig O., Grigoryan, Gevorg
Cyhoeddwyd yn Curr Opin Struct Biol (2017)

Modest membrane hydrogen bonds deliver rich results

gan Grigoryan, Gevorg, DeGrado, William F
Cyhoeddwyd 2008

Probing Designability via a Generalized Model of Helical Bundle Geometry

gan Grigoryan, Gevorg, DeGrado, William F.
Cyhoeddwyd 2010

Contact prediction is hardest for the most informative contacts, but improves with the incorporation of contact potentials

gan Holland, Jack, Pan, Qinxin, Grigoryan, Gevorg
Cyhoeddwyd yn PLoS One (2018)

Structure-based design of combinatorial mutagenesis libraries

gan Verma, Deeptak, Grigoryan, Gevorg, Bailey-Kellogg, Chris
Cyhoeddwyd yn Protein Sci (2015)

Tertiary alphabet for the observable protein structural universe

gan Mackenzie, Craig O., Zhou, Jianfu, Grigoryan, Gevorg
Cyhoeddwyd yn Proc Natl Acad Sci U S A (2016)

A general-purpose protein design framework based on mining sequence–structure relationships in known protein structures

gan Zhou, Jianfu, Panaitiu, Alexandra E., Grigoryan, Gevorg
Cyhoeddwyd yn Proc Natl Acad Sci U S A (2020)

Pareto optimization of combinatorial mutagenesis libraries

gan Verma, Deeptak, Grigoryan, Gevorg, Bailey-Kellogg, Chris
Cyhoeddwyd yn IEEE/ACM Trans Comput Biol Bioinform (2018)

Design of protein-interaction specificity affords selective bZIP-binding peptides

gan Grigoryan, Gevorg, Reinke, Aaron W., Keating, Amy E.
Cyhoeddwyd 2009

Identification of bZIP interaction partners of viral proteins HBZ, MEQ, BZLF1, and K-bZIP using coiled-coil arrays

gan Reinke, Aaron W., Grigoryan, Gevorg, Keating, Amy E.
Cyhoeddwyd 2010

Transmembrane Communication: General Principles and Lessons from the Structure and Function of the M2 Proton Channel, K(+) Channels, and Integrin Receptors

gan Grigoryan, Gevorg, Moore, David T., DeGrado, William F.
Cyhoeddwyd 2011

The accommodation index measures the perturbation associated with insertions and deletions in coiled‐coils: Application to understand signaling in histidine kinases

gan Schmidt, Nathan W., Grigoryan, Gevorg, DeGrado, William F.
Cyhoeddwyd yn Protein Sci (2017)

Design of self-assembling transmembrane helical bundles to elucidate principles required for membrane protein folding and ion transport

gan Joh, Nathan H., Grigoryan, Gevorg, Wu, Yibing, DeGrado, William F.
Cyhoeddwyd yn Philos Trans R Soc Lond B Biol Sci (2017)

Tertiary structural motif sequence statistics enable facile prediction and design of peptides that bind anti-apoptotic Bfl-1 and Mcl-1

gan Frappier, Vincent, Jenson, Justin M., Zhou, Jianfu, Grigoryan, Gevorg, Keating, Amy E.
Cyhoeddwyd yn Structure (2019)

Deletion of Na(+)/H(+) exchanger regulatory factor 2 represses colon cancer progress by suppression of Stat3 and CD24

gan Yoshida, Michihiro, Zhao, Luqing, Grigoryan, Gevorg, Shim, Hyunsuk, He, Peijian, Yun, C. Chris
Cyhoeddwyd yn Am J Physiol Gastrointest Liver Physiol (2016)

Computational Design of Selective Peptides to Discriminate Between Similar PDZ Domains in an Oncogenic Pathway

gan Zheng, Fan, Jewell, Heather, Fitzpatrick, Jeremy, Zhang, Jian, Mierke, Dale F., Grigoryan, Gevorg
Cyhoeddwyd yn J Mol Biol (2014)