Why is obesity associated with osteoarthritis? Insights from mouse models of obesity

Por Griffin, Timothy M., Guilak, Farshid
Publicado em 2008

Pathobiology of obesity and osteoarthritis: integrating biomechanics and inflammation

Por Issa, Rita I., Griffin, Timothy M.
Publicado em 2012

Insulin Resistance: Releasing the Brakes on Synovial Inflammation and Osteoarthritis?

Por Griffin, Timothy M., Huffman, Kim M.
Publicado no Arthritis Rheumatol (2016)

A novel mouse running wheel that senses individual limb forces: biomechanical validation and in vivo testing

Por Roach, Grahm C., Edke, Mangesh, Griffin, Timothy M.
Publicado no J Appl Physiol (1985) (2012)

Metabolic Regulation of Inflammation in Osteoarthritis

Por Berenbaum, Francis, Griffin, Timothy M., Liu-Bryan, Ru
Publicado no Arthritis Rheumatol (2017)

Calibration of a semi-automated segmenting method for quantification of adipose tissue compartments from magnetic resonance images of mice

Por Garteiser, Philippe, Doblas, Sabrina, Towner, Rheal A., Griffin, Timothy M.
Publicado em 2013

SWI/SNF Chromatin‐Remodeling Enzymes Brahma‐Related Gene 1 (BRG1) and Brahma (BRM) Are Dispensable in Multiple Models of Postnatal Angiogenesis But Are Required for Vascular Integr...

Por Wiley, Mandi M., Muthukumar, Vijay, Griffin, Timothy M., Griffin, Courtney T.
Publicado no J Am Heart Assoc (2015)

Extreme obesity due to impaired leptin signaling in mice does not cause knee osteoarthritis

Por Griffin, Timothy M., Huebner, Janet L., Kraus, Virginia B., Guilak, Farshid
Publicado em 2009

Locomotor activity and gait in aged mice deficient for type IX collagen

Por Costello, Kerry E., Guilak, Farshid, Setton, Lori A., Griffin, Timothy M.
Publicado em 2010

Increased susceptibility of Trpv4-Deficient Mice to Obesity and Obesity-Induced Osteoarthritis with Very High-Fat Diet

Por O’Conor, Christopher J., Griffin, Timothy M., Liedtke, Wolfgang, Guilak, Farshid
Publicado em 2012

Effect of Aging on Adipose Tissue Inflammation in the Knee Joints of F344BN Rats

Por Fu, Yao, Huebner, Janet L., Kraus, Virginia B., Griffin, Timothy M.
Publicado no J Gerontol A Biol Sci Med Sci (2016)

Emerging Role of Metabolic Signaling in Synovial Joint Remodeling and Osteoarthritis

Por June, Ronald K., Liu-Bryan, Ru, Long, Fanxing, Griffin, Timothy M.
Publicado no J Orthop Res (2016)

Induction of Osteoarthritis and Metabolic Inflammation by a Very High Fat Diet in Mice: Effects of Short-term Exercise

Por Griffin, Timothy M., Huebner, Janet L., Kraus, Virginia B., Yan, Zhen, Guilak, Farshid
Publicado em 2012

Mitochondrial respiration and redox coupling in articular chondrocytes

Por Lane, Rachel S, Fu, Yao, Matsuzaki, Satoshi, Kinter, Michael, Humphries, Kenneth M, Griffin, Timothy M
Publicado no Arthritis Res Ther (2015)

Nutrient Sensing and Utilization: Getting to the Heart of Metabolic Flexibility

Por Griffin, Timothy M., Humphries, Kenneth M., Kinter, Michael, Lim, Hui-Ying, Szweda, Luke I.
Publicado no Biochimie (2015)

Up-regulation of the Sirtuin 1 (Sirt1) and Peroxisome Proliferator-activated Receptor γ Coactivator-1α (PGC-1α) Genes in White Adipose Tissue of Id1 Protein-deficient Mice: IMPLICA...

Por Zhao, Ying, Ling, Flora, Griffin, Timothy M., He, Ting, Towner, Rheal, Ruan, Hong, Sun, Xiao-Hong
Publicado em 2014

Deficiency in adipocyte chemokine receptor CXCR4 exacerbates obesity and compromises thermoregulatory responses of brown adipose tissue in a mouse model of diet-induced obesity

Por Yao, Longbiao, Heuser-Baker, Janet, Herlea-Pana, Oana, Zhang, Nan, Szweda, Luke I., Griffin, Timothy M., Barlic-Dicen, Jana
Publicado em 2014

Aging Promotes SIRT3-dependent Cartilage SOD2 Acetylation and Osteoarthritis

Por Fu, Yao, Kinter, Michael, Hudson, Joanna, Humphries, Kenneth M., Lane, Rachel S., White, Jeremy R., Hakim, Michael, Pan, Yong, Verdin, Eric, Griffin, Timothy M.
Publicado no Arthritis Rheumatol (2016)

Decreased Physical Function and Increased Pain Sensitivity in Mice Deficient for Type IX Collagen

Por Allen, Kyle D., Griffin, Timothy M., Rodriguiz, Ramona M., Wetsel, William C., Kraus, Virginia B., Huebner, Janet L., Boyd, Lawrence M., Setton, Lori A.
Publicado em 2009

Diet-induced obesity differentially regulates behavioral, biomechanical, and molecular risk factors for osteoarthritis in mice

Por Griffin, Timothy M, Fermor, Beverley, Huebner, Janet L, Kraus, Virginia B, Rodriguiz, Ramona M, Wetsel, William C, Cao, Li, Setton, Lori A, Guilak, Farshid
Publicado em 2010