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Induction of Osteoarthritis and Metabolic Inflammation by a Very High Fat Diet in Mice: Effects of Short-term Exercise

OBJECTIVE: To test the hypotheses that obesity due to a very high fat diet induces knee osteoarthritis, and that short-term wheel running exercise protects against obesity-induced knee osteoarthritis by reducing systemic inflammation and metabolic dysregulation. METHODS: Male C57BL/6J mice were fed...

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Detalhes bibliográficos
Main Authors: Griffin, Timothy M., Huebner, Janet L., Kraus, Virginia B., Yan, Zhen, Guilak, Farshid
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3268860/
https://ncbi.nlm.nih.gov/pubmed/21953366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.33332
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