Diet-induced obesity differentially regulates behavioral, biomechanical, and molecular risk factors for osteoarthritis in mice

INTRODUCTION: Obesity is a major risk factor for the development of osteoarthritis in both weight-bearing and nonweight-bearing joints. The mechanisms by which obesity influences the structural or symptomatic features of osteoarthritis are not well understood, but may include systemic inflammation a...

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Autores principales: Griffin, Timothy M, Fermor, Beverley, Huebner, Janet L, Kraus, Virginia B, Rodriguiz, Ramona M, Wetsel, William C, Cao, Li, Setton, Lori A, Guilak, Farshid
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2010
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2945020/
https://ncbi.nlm.nih.gov/pubmed/20604941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3068
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