Why is obesity associated with osteoarthritis? Insights from mouse models of obesity

Por Griffin, Timothy M., Guilak, Farshid
Publicado em 2008

Pathobiology of obesity and osteoarthritis: integrating biomechanics and inflammation

Por Issa, Rita I., Griffin, Timothy M.
Publicado em 2012

Insulin Resistance: Releasing the Brakes on Synovial Inflammation and Osteoarthritis?

Por Griffin, Timothy M., Huffman, Kim M.
Publicado no Arthritis Rheumatol (2016)

Innate Inflammation and Synovial Macrophages in Osteoarthritis Pathophysiology

Por Griffin, Timothy M., Scanzello, Carla R.
Publicado no Clin Exp Rheumatol (2019)

A novel mouse running wheel that senses individual limb forces: biomechanical validation and in vivo testing

Por Roach, Grahm C., Edke, Mangesh, Griffin, Timothy M.
Publicado no J Appl Physiol (1985) (2012)

Metabolic Regulation of Inflammation in Osteoarthritis

Por Berenbaum, Francis, Griffin, Timothy M., Liu-Bryan, Ru
Publicado no Arthritis Rheumatol (2017)

Effect of biomechanical stress on endogenous antioxidant networks in bovine articular cartilage

Por Issa, Rita, Boeving, Michael, Kinter, Michael, Griffin, Timothy M.
Publicado no J Orthop Res (2017)

Calibration of a semi-automated segmenting method for quantification of adipose tissue compartments from magnetic resonance images of mice

Por Garteiser, Philippe, Doblas, Sabrina, Towner, Rheal A., Griffin, Timothy M.
Publicado em 2013

SWI/SNF Chromatin‐Remodeling Enzymes Brahma‐Related Gene 1 (BRG1) and Brahma (BRM) Are Dispensable in Multiple Models of Postnatal Angiogenesis But Are Required for Vascular Integr...

Por Wiley, Mandi M., Muthukumar, Vijay, Griffin, Timothy M., Griffin, Courtney T.
Publicado no J Am Heart Assoc (2015)

Glutathione as a Mediator of Cartilage Oxidative Stress Resistance and Resilience During Aging and Osteoarthritis

Por Zhu, Shouan, Makosa, Dawid, Miller, Benjamin F., Griffin, Timothy M.
Publicado no Connect Tissue Res (2019)

Extreme obesity due to impaired leptin signaling in mice does not cause knee osteoarthritis

Por Griffin, Timothy M., Huebner, Janet L., Kraus, Virginia B., Guilak, Farshid
Publicado em 2009

Locomotor activity and gait in aged mice deficient for type IX collagen

Por Costello, Kerry E., Guilak, Farshid, Setton, Lori A., Griffin, Timothy M.
Publicado em 2010

Increased susceptibility of Trpv4-Deficient Mice to Obesity and Obesity-Induced Osteoarthritis with Very High-Fat Diet

Por O’Conor, Christopher J., Griffin, Timothy M., Liedtke, Wolfgang, Guilak, Farshid
Publicado em 2012

Effect of Aging on Adipose Tissue Inflammation in the Knee Joints of F344BN Rats

Por Fu, Yao, Huebner, Janet L., Kraus, Virginia B., Griffin, Timothy M.
Publicado no J Gerontol A Biol Sci Med Sci (2016)

Emerging Role of Metabolic Signaling in Synovial Joint Remodeling and Osteoarthritis

Por June, Ronald K., Liu-Bryan, Ru, Long, Fanxing, Griffin, Timothy M.
Publicado no J Orthop Res (2016)

Correlation network analysis shows divergent effects of a long-term, high-fat diet and exercise on early stage osteoarthritis phenotypes in mice

Por Griffin, Timothy M., Batushansky, Albert, Hudson, Joanna, Lopes, Erika Barboza Prado
Publicado no J Sport Health Sci (2020)

Induction of Osteoarthritis and Metabolic Inflammation by a Very High Fat Diet in Mice: Effects of Short-term Exercise

Por Griffin, Timothy M., Huebner, Janet L., Kraus, Virginia B., Yan, Zhen, Guilak, Farshid
Publicado em 2012

Mitochondrial respiration and redox coupling in articular chondrocytes

Por Lane, Rachel S, Fu, Yao, Matsuzaki, Satoshi, Kinter, Michael, Humphries, Kenneth M, Griffin, Timothy M
Publicado no Arthritis Res Ther (2015)

Nutrient Sensing and Utilization: Getting to the Heart of Metabolic Flexibility

Por Griffin, Timothy M., Humphries, Kenneth M., Kinter, Michael, Lim, Hui-Ying, Szweda, Luke I.
Publicado no Biochimie (2015)

Independent effects of dietary fat and sucrose content on chondrocyte metabolism and osteoarthritis pathology in mice

Por Donovan, Elise L., Lopes, Erika Barboza Prado, Batushansky, Albert, Kinter, Mike, Griffin, Timothy M.
Publicado no Dis Model Mech (2018)