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Correlation network analysis shows divergent effects of a long-term, high-fat diet and exercise on early stage osteoarthritis phenotypes in mice

BACKGROUND: Obesity increases knee osteoarthritis (OA) risk through metabolic, inflammatory, and biomechanical factors, but how these systemic and local mediators interact to drive OA pathology is not well understood. We tested the effect of voluntary running exercise after chronic diet-induced obes...

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Pubblicato in:J Sport Health Sci
Autori principali: Griffin, Timothy M., Batushansky, Albert, Hudson, Joanna, Lopes, Erika Barboza Prado
Natura: Artigo
Lingua:Inglês
Pubblicazione: Shanghai University of Sport 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7031811/
https://ncbi.nlm.nih.gov/pubmed/32099720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jshs.2019.05.008
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