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Aging Promotes SIRT3-dependent Cartilage SOD2 Acetylation and Osteoarthritis
OBJECTIVE: To quantify functional age-related changes in the cartilage antioxidant network to discover novel mediators of cartilage oxidative stress and osteoarthritis (OA) pathophysiology. METHODS: We evaluated knee OA histopathology in 10, 20, and 30-month old male F344BN rats and analyzed cartila...
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| Publicado no: | Arthritis Rheumatol |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5331855/ https://ncbi.nlm.nih.gov/pubmed/26866626 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.39618 |
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