Refining our understanding of cervical neoplasia and its cellular origins

Por Doorbar, John, Griffin, Heather
Publicado no Papillomavirus Res (2019)

Implementing a successful data-management framework: the UK10K managed access model

Por Muddyman, Dawn, Smee, Carol, Griffin, Heather, Kaye, Jane
Publicado em 2013

Human Papillomaviruses; Epithelial Tropisms, and the Development of Neoplasia

Por Egawa, Nagayasu, Egawa, Kiyofumi, Griffin, Heather, Doorbar, John
Publicado no Viruses (2015)

Human papillomavirus molecular biology and disease association

Por Doorbar, John, Egawa, Nagayasu, Griffin, Heather, Kranjec, Christian, Murakami, Isao
Publicado no Rev Med Virol (2015)

Modulation of basal cell fate during productive and transforming HPV‐16 infection is mediated by progressive E6‐driven depletion of Notch

Por Kranjec, Christian, Holleywood, Christina, Libert, Diane, Griffin, Heather, Mahmood, Radma, Isaacson, Erin, Doorbar, John
Publicado no J Pathol (2017)

HPV16 and 18 genome amplification show different E4-dependence, with 16E4 enhancing E1 nuclear accumulation and replicative efficiency via its cell cycle arrest and kinase activati...

Por Egawa, Nagayasu, Wang, Qian, Griffin, Heather M., Murakami, Isao, Jackson, Deborah, Mahmood, Radma, Doorbar, John
Publicado no PLoS Pathog (2017)

Roles for E1-independent replication and E6-mediated p53 degradation during low-risk and high-risk human papillomavirus genome maintenance

Por Murakami, Isao, Egawa, Nagayasu, Griffin, Heather, Yin, Wen, Kranjec, Christian, Nakahara, Tomomi, Kiyono, Tohru, Doorbar, John
Publicado no PLoS Pathog (2019)

Reconstruction of Human Papillomavirus Type 16-Mediated Early-Stage Neoplasia Implicates E6/E7 Deregulation and the Loss of Contact Inhibition in Neoplastic Progression

Por Isaacson Wechsler, Erin, Wang, Qian, Roberts, Ian, Pagliarulo, Emilio, Jackson, Deborah, Untersperger, Christina, Coleman, Nick, Griffin, Heather, Doorbar, John
Publicado em 2012

Mutations in HPV18 E1^E4 Impact Virus Capsid Assembly, Infectivity Competence, and Maturation

Por Biryukov, Jennifer, Myers, Jocelyn C., McLaughlin-Drubin, Margaret E., Griffin, Heather M., Milici, Janice, Doorbar, John, Meyers, Craig
Publicado no Viruses (2017)

E1^E4-mediated keratin phosphorylation and ubiquitylation: a mechanism for keratin depletion in HPV16-infected epithelium

Por McIntosh, Pauline B., Laskey, Peter, Sullivan, Kate, Davy, Clare, Wang, Qian, Jackson, Deborah J., Griffin, Heather M., Doorbar, John
Publicado em 2010

Human papillomavirus type 16 causes a defined subset of conjunctival in situ squamous cell carcinomas

Por Griffin, Heather, Mudhar, Hardeep Singh, Rundle, Paul, Shiraz, Aslam, Mahmood, Radma, Egawa, Nagayasu, Quint, Wim, Rennie, Ian G., Doorbar, John
Publicado no Mod Pathol (2019)

Risk stratification of cervical disease using detection of human papillomavirus (HPV) E4 protein and cellular MCM protein in clinical liquid based cytology samples

Por Stevenson, Andrew, Kavanagh, Kim, Pan, Jiafeng, Stevenson, Lynne, Griffin, Heather, Doorbar, John, Scott, Evelyn, Deeny, Miriam, Cuschieri, Kate, Graham, Sheila V.
Publicado no J Clin Virol (2018)

E4 Antibodies Facilitate Detection and Type-Assignment of Active HPV Infection in Cervical Disease

Por Griffin, Heather, Wu, Zhonglin, Marnane, Rebecca, Dewar, Vincent, Molijn, Anco, Quint, Wim, Van Hoof, Christine, Struyf, Frank, Colau, Brigitte, Jenkins, David, Doorbar, John
Publicado em 2012

Whole tissue cervical mapping of HPV infection: Molecular evidence for focal latent HPV infection in humans

Por Hammer, Anne, de Koning, Maurits NC, Blaakaer, Jan, Steiniche, Torben, Doorbar, John, Griffin, Heather, Mejlgaard, Else, Svanholm, Hans, Quint, Wim GV, Gravitt, Patti E.
Publicado no Papillomavirus Res (2019)

The E1∧E4 Protein of Human Papillomavirus Type 16 Associates with a Putative RNA Helicase through Sequences in Its C Terminus

Por Doorbar, John, Elston, Robert C., Napthine, Sawsan, Raj, Kenneth, Medcalf, Elizabeth, Jackson, Deborah, Coleman, Nick, Griffin, Heather M., Masterson, Philip, Stacey, Simon, Mengistu, Yohannes, Dunlop, Julia
Publicado em 2000

Functional Analysis of the Human Papillomavirus Type 16 E1(∧)E4 Protein Provides a Mechanism for In Vivo and In Vitro Keratin Filament Reorganization

Por Wang, Qian, Griffin, Heather, Southern, Shirley, Jackson, Deborah, Martin, Ana, McIntosh, Pauline, Davy, Clare, Masterson, Phillip J., Walker, Philip A., Laskey, Peter, Omary, M. Bishr, Doorbar, John
Publicado em 2004

Organization of Human Papillomavirus Productive Cycle during Neoplastic Progression Provides a Basis for Selection of Diagnostic Markers

Por Middleton, Kate, Peh, Woei, Southern, Shirley, Griffin, Heather, Sotlar, Karl, Nakahara, Tomomi, El-Sherif, Amira, Morris, Lesley, Seth, Rashmi, Hibma, Merilyn, Jenkins, David, Lambert, Paul, Coleman, Nicholas, Doorbar, John
Publicado em 2003

Stratification of HPV-Induced Cervical Pathology using the Virally-Encoded Molecular Marker E4 in Combination with p16 or MCM

Por Griffin, Heather, Soneji, Yasmina, Van Baars, Romy, Arora, Rupali, Jenkins, David, van de Sandt, Miekel, Wu, Zhonglin, Quint, Wim, Jach, Robert, Okon, Krzysztof, Huras, Hubert, Singer, Albert, Doorbar, John
Publicado no Mod Pathol (2015)

Structural Analysis Reveals an Amyloid Form of the Human Papillomavirus Type 16 E1(∧)E4 Protein and Provides a Molecular Basis for Its Accumulation

Por McIntosh, Pauline B., Martin, Stephen R., Jackson, Deborah J., Khan, Jameela, Isaacson, Erin R., Calder, Lesley, Raj, Kenneth, Griffin, Heather M., Wang, Qian, Laskey, Peter, Eccleston, John F., Doorbar, John
Publicado em 2008

The Role of Human Papillomaviruses and Polyomaviruses in BRAF-Inhibitor Induced Cutaneous Squamous Cell Carcinoma and Benign Squamoproliferative Lesions

Por Purdie, Karin J., Proby, Charlotte M., Rizvi, Hasan, Griffin, Heather, Doorbar, John, Sommerlad, Mary, Feltkamp, Mariet C., der Meijden, Els Van, Inman, Gareth J., South, Andrew P., Leigh, Irene M., Harwood, Catherine A.
Publicado no Front Microbiol (2018)