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Functional Analysis of the Human Papillomavirus Type 16 E1(∧)E4 Protein Provides a Mechanism for In Vivo and In Vitro Keratin Filament Reorganization

High-risk human papillomaviruses, such as human papillomavirus type 16 (HPV16), are the primary cause of cervical cancer. The HPV16 E1(∧)E4 protein associates with keratin intermediate filaments and causes network collapse when expressed in epithelial cells in vitro. Here, we show that keratin assoc...

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Autori principali: Wang, Qian, Griffin, Heather, Southern, Shirley, Jackson, Deborah, Martin, Ana, McIntosh, Pauline, Davy, Clare, Masterson, Phillip J., Walker, Philip A., Laskey, Peter, Omary, M. Bishr, Doorbar, John
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC368840/
https://ncbi.nlm.nih.gov/pubmed/14694114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.2.821-833.2004
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