E1^E4-mediated keratin phosphorylation and ubiquitylation: a mechanism for keratin depletion in HPV16-infected epithelium

The keratin IF network of epidermal keratinocytes provides a protective barrier against mechanical insult, it is also a major player in absorbing stress in these cells. The human papilloma virus (HPV) type 16 E1^E4 protein accumulates in the upper layers of HPV16-infected epithelium and is known to...

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Bibliographic Details
Main Authors: McIntosh, Pauline B., Laskey, Peter, Sullivan, Kate, Davy, Clare, Wang, Qian, Jackson, Deborah J., Griffin, Heather M., Doorbar, John
Format: Artigo
Language:Inglês
Published: Company of Biologists 2010
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2915882/
https://ncbi.nlm.nih.gov/pubmed/20663917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.061978
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