Roles for E1-independent replication and E6-mediated p53 degradation during low-risk and high-risk human papillomavirus genome maintenance

Human papillomaviruses (HPV) have genotype-specific disease associations, with high-risk alpha types causing at least 5% of all human cancers. Despite these conspicuous differences, our data show that high- and low- risk HPV types use similar approaches for genome maintenance and persistence. During...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Murakami, Isao, Egawa, Nagayasu, Griffin, Heather, Yin, Wen, Kranjec, Christian, Nakahara, Tomomi, Kiyono, Tohru, Doorbar, John
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6544336/
https://ncbi.nlm.nih.gov/pubmed/31083694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007755
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