The E1 Protein of Human Papillomavirus Type 16 Is Dispensable for Maintenance Replication of the Viral Genome

Papillomavirus genomes are thought to be amplified to about 100 copies per cell soon after infection, maintained constant at this level in basal cells, and amplified for viral production upon keratinocyte differentiation. To determine the requirement for E1 in viral DNA replication at different stag...

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Autores principales: Egawa, Nagayasu, Nakahara, Tomomi, Ohno, Shin-ichi, Narisawa-Saito, Mako, Yugawa, Takashi, Fujita, Masatoshi, Yamato, Kenji, Natori, Yukikazu, Kiyono, Tohru
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2012
Materias:
Genome Replication and Regulation of Viral Gene Expression
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302310/
https://ncbi.nlm.nih.gov/pubmed/22238312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06450-11
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