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E6AP-Dependent Degradation of DLG4/PSD95 by High-Risk Human Papillomavirus Type 18 E6 Protein

In most cervical cancers, DNAs of high-risk mucosotropic human papillomaviruses (HPVs), such as types 16 and 18, are maintained so as to express two viral proteins, E6 and E7, suggesting that they play important roles in carcinogenesis. The carboxy-terminal PDZ domain-binding motif of the E6 protein...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Handa, Keisuke, Yugawa, Takashi, Narisawa-Saito, Mako, Ohno, Shin-ichi, Fujita, Masatoshi, Kiyono, Tohru
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797514/
https://ncbi.nlm.nih.gov/pubmed/17121805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01712-06
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