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Human Papillomavirus 16 E6 Upregulates APOBEC3B via the TEAD Transcription Factor

The cytidine deaminase APOBEC3B (A3B) underlies the genetic heterogeneity of several human cancers, including cervical cancer, which is caused by human papillomavirus (HPV) infection. We previously identified a region within the A3B promoter that is activated by the viral protein HPV16 E6 in human k...

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Publicado en:J Virol
Autores principales: Mori, Seiichiro, Takeuchi, Takamasa, Ishii, Yoshiyuki, Yugawa, Takashi, Kiyono, Tohru, Nishina, Hiroshi, Kukimoto, Iwao
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5331809/
https://ncbi.nlm.nih.gov/pubmed/28077648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02413-16
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