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Human Papillomavirus 16 E6 Upregulates APOBEC3B via the TEAD Transcription Factor

The cytidine deaminase APOBEC3B (A3B) underlies the genetic heterogeneity of several human cancers, including cervical cancer, which is caused by human papillomavirus (HPV) infection. We previously identified a region within the A3B promoter that is activated by the viral protein HPV16 E6 in human k...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Mori, Seiichiro, Takeuchi, Takamasa, Ishii, Yoshiyuki, Yugawa, Takashi, Kiyono, Tohru, Nishina, Hiroshi, Kukimoto, Iwao
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5331809/
https://ncbi.nlm.nih.gov/pubmed/28077648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02413-16
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