Within-Host Variations of Human Papillomavirus Reveal APOBEC Signature Mutagenesis in the Viral Genome

Persistent infection with oncogenic human papillomaviruses (HPVs) causes cervical cancer, accompanied by the accumulation of somatic mutations into the host genome. There are concomitant genetic changes in the HPV genome during viral infection; however, their relevance to cervical carcinogenesis is...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Hirose, Yusuke, Onuki, Mamiko, Tenjimbayashi, Yuri, Mori, Seiichiro, Ishii, Yoshiyuki, Takeuchi, Takamasa, Tasaka, Nobutaka, Satoh, Toyomi, Morisada, Tohru, Iwata, Takashi, Miyamoto, Shingo, Matsumoto, Koji, Sekizawa, Akihiko, Kukimoto, Iwao
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Genetic Diversity and Evolution
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5974501/
https://ncbi.nlm.nih.gov/pubmed/29593040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00017-18
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