Within-Host Variations of Human Papillomavirus Reveal APOBEC Signature Mutagenesis in the Viral Genome

Persistent infection with oncogenic human papillomaviruses (HPVs) causes cervical cancer, accompanied by the accumulation of somatic mutations into the host genome. There are concomitant genetic changes in the HPV genome during viral infection; however, their relevance to cervical carcinogenesis is...

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書目詳細資料
發表在:J Virol
Main Authors: Hirose, Yusuke, Onuki, Mamiko, Tenjimbayashi, Yuri, Mori, Seiichiro, Ishii, Yoshiyuki, Takeuchi, Takamasa, Tasaka, Nobutaka, Satoh, Toyomi, Morisada, Tohru, Iwata, Takashi, Miyamoto, Shingo, Matsumoto, Koji, Sekizawa, Akihiko, Kukimoto, Iwao
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2018
主題:
Genetic Diversity and Evolution
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5974501/
https://ncbi.nlm.nih.gov/pubmed/29593040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00017-18
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