Within-Host Variations of Human Papillomavirus Reveal APOBEC Signature Mutagenesis in the Viral Genome

Persistent infection with oncogenic human papillomaviruses (HPVs) causes cervical cancer, accompanied by the accumulation of somatic mutations into the host genome. There are concomitant genetic changes in the HPV genome during viral infection; however, their relevance to cervical carcinogenesis is...

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Bibliografiset tiedot
Julkaisussa:J Virol
Päätekijät: Hirose, Yusuke, Onuki, Mamiko, Tenjimbayashi, Yuri, Mori, Seiichiro, Ishii, Yoshiyuki, Takeuchi, Takamasa, Tasaka, Nobutaka, Satoh, Toyomi, Morisada, Tohru, Iwata, Takashi, Miyamoto, Shingo, Matsumoto, Koji, Sekizawa, Akihiko, Kukimoto, Iwao
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2018
Aiheet:
Genetic Diversity and Evolution
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5974501/
https://ncbi.nlm.nih.gov/pubmed/29593040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00017-18
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