Within-Host Variations of Human Papillomavirus Reveal APOBEC Signature Mutagenesis in the Viral Genome

Persistent infection with oncogenic human papillomaviruses (HPVs) causes cervical cancer, accompanied by the accumulation of somatic mutations into the host genome. There are concomitant genetic changes in the HPV genome during viral infection; however, their relevance to cervical carcinogenesis is...

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Dettagli Bibliografici
Pubblicato in:J Virol
Autori principali: Hirose, Yusuke, Onuki, Mamiko, Tenjimbayashi, Yuri, Mori, Seiichiro, Ishii, Yoshiyuki, Takeuchi, Takamasa, Tasaka, Nobutaka, Satoh, Toyomi, Morisada, Tohru, Iwata, Takashi, Miyamoto, Shingo, Matsumoto, Koji, Sekizawa, Akihiko, Kukimoto, Iwao
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2018
Soggetti:
Genetic Diversity and Evolution
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5974501/
https://ncbi.nlm.nih.gov/pubmed/29593040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00017-18
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