Within-Host Variations of Human Papillomavirus Reveal APOBEC Signature Mutagenesis in the Viral Genome

Persistent infection with oncogenic human papillomaviruses (HPVs) causes cervical cancer, accompanied by the accumulation of somatic mutations into the host genome. There are concomitant genetic changes in the HPV genome during viral infection; however, their relevance to cervical carcinogenesis is...

Full description

Saved in:
Bibliographic Details
Published in:J Virol
Main Authors: Hirose, Yusuke, Onuki, Mamiko, Tenjimbayashi, Yuri, Mori, Seiichiro, Ishii, Yoshiyuki, Takeuchi, Takamasa, Tasaka, Nobutaka, Satoh, Toyomi, Morisada, Tohru, Iwata, Takashi, Miyamoto, Shingo, Matsumoto, Koji, Sekizawa, Akihiko, Kukimoto, Iwao
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2018
Subjects:
Genetic Diversity and Evolution
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5974501/
https://ncbi.nlm.nih.gov/pubmed/29593040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00017-18
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items