Quantitative Prediction of Drug–Drug Interactions Involving Inhibitory Metabolites by Physiologically Based Pharmacokinetic Models: Is it Worth It?

Por Tod, M, Goutelle, S, Bourguignon, L, Bleyzac, N
Publicado no CPT Pharmacometrics Syst Pharmacol (2017)

A pharmacometric pulmonary model predicting the extent and rate of distribution from plasma to epithelial lining fluid and alveolar cells—using rifampicin as an example

Por Clewe, Oskar, Goutelle, Sylvain, Conte, John E., Simonsson, Ulrika S. H.
Publicado no Eur J Clin Pharmacol (2015)

Mechanisms of drug–drug interaction between rifampicin and fusidic acid

Por Bel, Florianne, Bourguignon, Laurent, Tod, Michel, Ferry, Tristan, Goutelle, Sylvain
Publicado no Br J Clin Pharmacol (2017)

Population Modeling and Simulation Study of the Pharmacokinetics and Antituberculosis Pharmacodynamics of Isoniazid in Lungs

Por Lalande, L., Bourguignon, L., Bihari, S., Maire, P., Neely, M., Jelliffe, R., Goutelle, S.
Publicado no Antimicrob Agents Chemother (2015)

Model-Based Determination of Effective Blood Concentrations of Cyclosporine for Neutrophil Response in the Treatment of Severe Aplastic Anemia in Children

Por Philippe, Michaël, Hénin, Emilie, Bertrand, Yves, Plantaz, Dominique, Goutelle, Sylvain, Bleyzac, Nathalie
Publicado no AAPS J (2015)

Pharmacokinetics of Vancomycin in Elderly Patients Aged over 80 Years

Por Bourguignon, Laurent, Cazaubon, Yoann, Debeurme, Guillaume, Loue, Constance, Ducher, Michel, Goutelle, Sylvain
Publicado no Antimicrob Agents Chemother (2016)

The Role of Antibiotics in Modulating Virulence in Staphylococcus aureus

Por Hodille, Elisabeth, Rose, Warren, Diep, Binh An, Goutelle, Sylvain, Lina, Gerard, Dumitrescu, Oana
Publicado no Clin Microbiol Rev (2017)

Assessing the Combined Antibacterial Effect of Isoniazid and Rifampin on Four Mycobacterium tuberculosis Strains Using In Vitro Experiments and Response-Surface Modeling

Por Genestet, Charlotte, Ader, Florence, Pichat, Catherine, Lina, Gérard, Dumitrescu, Oana, Goutelle, Sylvain
Publicado no Antimicrob Agents Chemother (2017)

In Vivo Quantitative Prediction of the Effect of Gene Polymorphisms and Drug Interactions on Drug Exposure for CYP2C19 Substrates

Por Goutelle, Sylvain, Bourguignon, Laurent, Bleyzac, Nathalie, Berry, Johanna, Clavel-Grabit, Fannie, Tod, Michel
Publicado em 2013

Comparison of Four Renal Function Estimation Equations for Pharmacokinetic Modeling of Gentamicin in Geriatric Patients

Por Charhon, Nicolas, Neely, Michael N., Bourguignon, Laurent, Maire, Pascal, Jelliffe, Roger W., Goutelle, Sylvain
Publicado em 2012

Influence of Renal Function Estimation on Pharmacokinetic Modeling of Vancomycin in Elderly Patients

Por Glatard, Anaïs, Bourguignon, Laurent, Jelliffe, Roger W., Maire, Pascal, Neely, Michael N., Goutelle, Sylvain
Publicado no Antimicrob Agents Chemother (2015)

Population Modeling and Monte Carlo Simulation Study of the Pharmacokinetics and Antituberculosis Pharmacodynamics of Rifampin in Lungs

Por Goutelle, Sylvain, Bourguignon, Laurent, Maire, Pascal H., Van Guilder, Michael, Conte, John E., Jelliffe, Roger W.
Publicado em 2009

Population Pharmacokinetic Study of Amoxicillin-Treated Burn Patients Hospitalized at a Swiss Tertiary-Care Center

Por Fournier, Anne, Goutelle, Sylvain, Que, Yok-Ai, Eggimann, Philippe, Pantet, Olivier, Sadeghipour, Farshid, Voirol, Pierre, Csajka, Chantal
Publicado no Antimicrob Agents Chemother (2018)

Pharmacokinetic Variability of Daptomycin during Prolonged Therapy for Bone and Joint Infections

Por Goutelle, Sylvain, Roux, Sandrine, Gagnieu, Marie-Claude, Valour, Florent, Lustig, Sébastien, Ader, Florence, Laurent, Frédéric, Chidiac, Christian, Ferry, Tristan
Publicado no Antimicrob Agents Chemother (2016)

Accurately achieving target busulfan exposure in children and adolescents with very limited sampling and the BestDose software

Por Neely, Michael, Philippe, Michael, Rushing, Teresa, Fu, Xiaowei, van Guilder, Michael, Bayard, David, Schumitzky, Alan, Bleyzac, Nathalie, Goutelle, Sylvain
Publicado no Ther Drug Monit (2016)

Pharmacokinetic-Pharmacodynamic Modeling of Unboosted Atazanavir in a Cohort of Stable HIV-Infected Patients

Por Goutelle, Sylvain, Baudry, Thomas, Gagnieu, Marie-Claude, Boibieux, André, Livrozet, Jean-Michel, Peyramond, Dominique, Chidiac, Christian, Tod, Michel, Ferry, Tristan
Publicado em 2013

Prospective Cohort Study of the Tolerability of Prosthetic Joint Infection Empirical Antimicrobial Therapy

Por Triffault-Fillit, Claire, Valour, Florent, Guillo, Ronan, Tod, Michel, Goutelle, Sylvain, Lustig, Sébastien, Fessy, Michel-Henry, Chidiac, Christian, Ferry, Tristan
Publicado no Antimicrob Agents Chemother (2018)

Intrapulmonary Pharmacokinetics and Pharmacodynamics of Micafungin in Adult Lung Transplant Patients

Por Walsh, Thomas J., Goutelle, Sylvain, Jelliffe, Roger W., Golden, Jeffrey A., Little, Emily A., DeVoe, Catherine, Mickiene, Diana, Hayes, Maggie, Conte, John E.
Publicado em 2010

Subcutaneous Suppressive Antibiotic Therapy for Bone and Joints Infections: Safety and Outcome in a Cohort of 10 Patients

Por Ferry, Tristan, Pouderoux, Cecile, Goutelle, Sylvain, Lustig, Sébastien, Triffault-Fillit, Claire, Daoud, Fatiha, Fessy, Michel-Henri, Cohen, Sabine, Laurent, Frederic, Chidiac, Christian, Valour, Florent
Publicado no Open Forum Infect Dis (2017)

Optimization of the treatment with beta-lactam antibiotics in critically ill patients—guidelines from the French Society of Pharmacology and Therapeutics (Société Française de Phar...

Por Guilhaumou, Romain, Benaboud, Sihem, Bennis, Youssef, Dahyot-Fizelier, Claire, Dailly, Eric, Gandia, Peggy, Goutelle, Sylvain, Lefeuvre, Sandrine, Mongardon, Nicolas, Roger, Claire, Scala-Bertola, Julien, Lemaitre, Florian, Garnier, Marc
Publicado no Crit Care (2019)