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Comparison of Four Renal Function Estimation Equations for Pharmacokinetic Modeling of Gentamicin in Geriatric Patients

Most aminoglycoside pharmacokinetic models include an index of renal function, such as creatinine clearance, to describe drug clearance. However, the best clinical descriptor of renal function for the pharmacokinetic modeling of aminoglycosides has not been established. This analysis was based on 41...

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Detalhes bibliográficos
Main Authors: Charhon, Nicolas, Neely, Michael N., Bourguignon, Laurent, Maire, Pascal, Jelliffe, Roger W., Goutelle, Sylvain
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318363/
https://ncbi.nlm.nih.gov/pubmed/22290966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05634-11
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