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Comparison of Four Renal Function Estimation Equations for Pharmacokinetic Modeling of Gentamicin in Geriatric Patients

Most aminoglycoside pharmacokinetic models include an index of renal function, such as creatinine clearance, to describe drug clearance. However, the best clinical descriptor of renal function for the pharmacokinetic modeling of aminoglycosides has not been established. This analysis was based on 41...

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Главные авторы: Charhon, Nicolas, Neely, Michael N., Bourguignon, Laurent, Maire, Pascal, Jelliffe, Roger W., Goutelle, Sylvain
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318363/
https://ncbi.nlm.nih.gov/pubmed/22290966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05634-11
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