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Comparison of Four Renal Function Estimation Equations for Pharmacokinetic Modeling of Gentamicin in Geriatric Patients

Most aminoglycoside pharmacokinetic models include an index of renal function, such as creatinine clearance, to describe drug clearance. However, the best clinical descriptor of renal function for the pharmacokinetic modeling of aminoglycosides has not been established. This analysis was based on 41...

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Bibliografiske detaljer
Main Authors: Charhon, Nicolas, Neely, Michael N., Bourguignon, Laurent, Maire, Pascal, Jelliffe, Roger W., Goutelle, Sylvain
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318363/
https://ncbi.nlm.nih.gov/pubmed/22290966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05634-11
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