Goodbye to the bioassay

par Goodman, Jay I.
Publié dans Toxicol Res (Camb) (2018)

Correction: Goodbye to the bioassay

par Goodman, Jay I.
Publié dans Toxicol Res (Camb) (2018)

Incorporation of an Epigenetic Evaluation into Safety Assessment: What we First Need to Know

par Goodman, Jay I.
Publié dans Curr Opin Toxicol (2017)

Multiple Genes Exhibit Phenobarbital-Induced Constitutive Active/Androstane Receptor–Mediated DNA Methylation Changes during Liver Tumorigenesis and in Liver Tumors

par Phillips, Jennifer M., Goodman, Jay I.
Publié 2009

In Memoriam: Jerry B. Hook (1938 –2021)

par Goodman, Jay I, Kaminski, Norbert E
Publié dans Toxicol Sci (2021)

Phenobarbital Elicits Unique, Early Changes in the Expression of Hepatic Genes that Affect Critical Pathways in Tumor-Prone B6C3F1 Mice

par Phillips, Jennifer M., Burgoon, Lyle D., Goodman, Jay I.
Publié 2009

The Constitutive Active/Androstane Receptor Facilitates Unique Phenobarbital-Induced Expression Changes of Genes Involved in Key Pathways in Precancerous Liver and Liver Tumors

par Phillips, Jennifer M., Burgoon, Lyle D., Goodman, Jay I.
Publié 2009

Changes in DNA Methylation and Gene Expression during 2,3,7,8-Tetrachlorodibenzo-p-dioxin-Induced Suppression of the Lipopolysaccharide-Stimulated IgM Response in Splenocytes

par McClure, Emily A., North, Colin M., Kaminski, Norbert E., Goodman, Jay I.
Publié 2011

Phenobarbital and propiconazole toxicogenomic profiles in mice show major similarities consistent with the key role that constitutive androstane receptor (CAR) activation plays in...

par Currie, Richard A., Peffer, Richard C., Goetz, Amber K., Omiecinski, Curtis J., Goodman, Jay I.
Publié 2014

Computational modeling identifies key gene regulatory interactions underlying phenobarbital-mediated tumor promotion

par Luisier, Raphaëlle, Unterberger, Elif B., Goodman, Jay I., Schwarz, Michael, Moggs, Jonathan, Terranova, Rémi, van Nimwegen, Erik
Publié 2014

Illustrative case using the RISK21 roadmap and matrix: prioritization for evaluation of chemicals found in drinking water

par Wolf, Douglas C., Bachman, Ammie, Barrett, Gordon, Bellin, Cheryl, Goodman, Jay I., Jensen, Elke, Moretto, Angelo, McMullin, Tami, Pastoor, Timothy P., Schoeny, Rita, Slezak, Brian, Wend, Korinna, Embry, Michelle R.
Publié dans Crit Rev Toxicol (2016)

Mode of action and human relevance analysis for nuclear receptor-mediated liver toxicity: A case study with phenobarbital as a model constitutive androstane receptor (CAR) activato...

par Elcombe, Clifford R., Peffer, Richard C., Wolf, Douglas C., Bailey, Jason, Bars, Remi, Bell, David, Cattley, Russell C., Ferguson, Stephen S., Geter, David, Goetz, Amber, Goodman, Jay I., Hester, Susan, Jacobs, Abigail, Omiecinski, Curtis J., Schoeny, Rita, Xie, Wen, Lake, Brian G.
Publié 2013