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The Constitutive Active/Androstane Receptor Facilitates Unique Phenobarbital-Induced Expression Changes of Genes Involved in Key Pathways in Precancerous Liver and Liver Tumors

Our overall goal is to elucidate progressive changes, in expression and methylation status, of genes which play key roles in phenobarbital (PB)–induced liver tumorigenesis, with an emphasis on their potential to affect signaling through critical pathways involved in the regulation of cell growth and...

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Detalhes bibliográficos
Main Authors: Phillips, Jennifer M., Burgoon, Lyle D., Goodman, Jay I.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2708600/
https://ncbi.nlm.nih.gov/pubmed/19482888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfp108
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