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Changes in DNA Methylation and Gene Expression during 2,3,7,8-Tetrachlorodibenzo-p-dioxin-Induced Suppression of the Lipopolysaccharide-Stimulated IgM Response in Splenocytes

Lipopolysaccharide (LPS) is a bacterial endotoxin and a potent B-cell activator capable of inducing a humoral immune response. 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is a well-established immunotoxicant that can suppress humoral immune responses, including those initiated by LPS stimulation. In...

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Hlavní autoři: McClure, Emily A., North, Colin M., Kaminski, Norbert E., Goodman, Jay I.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3061478/
https://ncbi.nlm.nih.gov/pubmed/21212295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfq396
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