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Changes in DNA Methylation and Gene Expression during 2,3,7,8-Tetrachlorodibenzo-p-dioxin-Induced Suppression of the Lipopolysaccharide-Stimulated IgM Response in Splenocytes
Lipopolysaccharide (LPS) is a bacterial endotoxin and a potent B-cell activator capable of inducing a humoral immune response. 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is a well-established immunotoxicant that can suppress humoral immune responses, including those initiated by LPS stimulation. In...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3061478/ https://ncbi.nlm.nih.gov/pubmed/21212295 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfq396 |
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