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2,3,7,8-Tetrachlorodibenzo-p-dioxin–Mediated Suppression of Toll-Like Receptor Stimulated B-Lymphocyte Activation and Initiation of Plasmacytic Differentiation

2,3,7,8-Tetrachlordibenzo-p-dioxin (TCDD) is a potent suppressor of humoral immunity, disrupting antibody production in response to both T cell–dependent and T cell–independent antigens. Among the cell types required for humoral responses, the B cell is highly, and directly, sensitive to TCDD. B cel...

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Detalhes bibliográficos
Main Authors: North, Colin M., Crawford, Robert B., Lu, Haitian, Kaminski, Norbert E.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2886857/
https://ncbi.nlm.nih.gov/pubmed/20348231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfq095
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