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Induction of the Aryl Hydrocarbon Receptor–Responsive Genes and Modulation of the Immunoglobulin M Response by 2,3,7,8-Tetrachlorodibenzo-p-Dioxin in Primary Human B Cells

Past studies in rodent models identified the suppression of primary humoral immune responses as one of the most sensitive sequela associated with 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) exposure. Yet, the sensitivity of humoral immunity to TCDD in humans represents an important toxicological data...

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Main Authors: Lu, Haitian, Crawford, Robert B., Suarez-Martinez, Jose E., Kaplan, Barbara L. F., Kaminski, Norbert E.
格式: Artigo
語言:Inglês
出版: Oxford University Press 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2955211/
https://ncbi.nlm.nih.gov/pubmed/20702590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfq234
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