Circuits of cancer drivers revealed by convergent misregulation of transcription factor targets across tumor types

Por Gonzalez-Perez, Abel
Publicado no Genome Med (2016)

Improving the Assessment of the Outcome of Nonsynonymous SNVs with a Consensus Deleteriousness Score, Condel

Por González-Pérez, Abel, López-Bigas, Nuria
Publicado em 2011

Functional impact bias reveals cancer drivers

Por Gonzalez-Perez, Abel, Lopez-Bigas, Nuria
Publicado em 2012

Oncodrive-CIS: A Method to Reveal Likely Driver Genes Based on the Impact of Their Copy Number Changes on Expression

Por Tamborero, David, Lopez-Bigas, Nuria, Gonzalez-Perez, Abel
Publicado em 2013

Visualizing multidimensional cancer genomics data

Por Schroeder, Michael P, Gonzalez-Perez, Abel, Lopez-Bigas, Nuria
Publicado em 2013

The mutational landscape of chromatin regulatory factors across 4,623 tumor samples

Por Gonzalez-Perez, Abel, Jene-Sanz, Alba, Lopez-Bigas, Nuria
Publicado em 2013

Improving the prediction of the functional impact of cancer mutations by baseline tolerance transformation

Por Gonzalez-Perez, Abel, Deu-Pons, Jordi, Lopez-Bigas, Nuria
Publicado em 2012

Uncovering disease mechanisms through network biology in the era of Next Generation Sequencing

Por Piñero, Janet, Berenstein, Ariel, Gonzalez-Perez, Abel, Chernomoretz, Ariel, Furlong, Laura I.
Publicado no Sci Rep (2016)

Altered oncomodules underlie chromatin regulatory factors driver mutations

Por Frigola, Joan, Iturbide, Ane, Lopez-Bigas, Nuria, Peiro, Sandra, Gonzalez-Perez, Abel
Publicado no Oncotarget (2016)

From sequence to dynamics: the effects of transcription factor and polymerase concentration changes on activated and repressed promoters

Por González Pérez, Abel, Espinosa Angarica, Vladimir, Collado-Vides, Julio, Vasconcelos, Ana Tereza Ribeiro
Publicado em 2009

OncodriveFML: a general framework to identify coding and non-coding regions with cancer driver mutations

Por Mularoni, Loris, Sabarinathan, Radhakrishnan, Deu-Pons, Jordi, Gonzalez-Perez, Abel, López-Bigas, Núria
Publicado no Genome Biol (2016)

OncodriveROLE classifies cancer driver genes in loss of function and activating mode of action

Por Schroeder, Michael P., Rubio-Perez, Carlota, Tamborero, David, Gonzalez-Perez, Abel, Lopez-Bigas, Nuria
Publicado em 2014

Rational design of cancer gene panels with OncoPaD

Por Rubio-Perez, Carlota, Deu-Pons, Jordi, Tamborero, David, Lopez-Bigas, Nuria, Gonzalez-Perez, Abel
Publicado no Genome Med (2016)

Impact of Transcription Units rearrangement on the evolution of the regulatory network of gamma-proteobacteria

Por González Pérez, Abel D, González González, Evelyn, Espinosa Angarica, Vladimir, Vasconcelos, Ana Tereza R, Collado-Vides, Julio
Publicado em 2008

PARADIGM-SHIFT predicts the function of mutations in multiple cancers using pathway impact analysis

Por Ng, Sam, Collisson, Eric A., Sokolov, Artem, Goldstein, Theodore, Gonzalez-Perez, Abel, Lopez-Bigas, Nuria, Benz, Christopher, Haussler, David, Stuart, Joshua M.
Publicado em 2012

Comprehensive identification of mutational cancer driver genes across 12 tumor types

Por Tamborero, David, Gonzalez-Perez, Abel, Perez-Llamas, Christian, Deu-Pons, Jordi, Kandoth, Cyriac, Reimand, Jüri, Lawrence, Michael S., Getz, Gad, Bader, Gary D., Ding, Li, Lopez-Bigas, Nuria
Publicado em 2013

Cytoplasmic accumulation of NCoR in malignant melanoma: consequences of altered gene repression and prognostic significance

Por Gallardo, Fernando, Padrón, Andreina, Garcia-Carbonell, Ricard, Rius, Cristina, González-Perez, Abel, Arumí-Uria, Montserrat, Iglesias, Mar, Nonell, Lara, Bellosillo, Beatriz, Segura, Sonia, Pujol, Ramon Maria, Lopez-Bigas, Nuria, Bertran, Joan, Bigas, Anna, Espinosa, Lluís
Publicado no Oncotarget (2015)

Non-canonical NF-κB pathway activation predicts outcome in borderline oestrogen receptor positive breast carcinoma

Por Rojo, Federico, González-Pérez, Abel, Furriol, Jessica, Nicolau, Ma Jesús, Ferrer, Jaime, Burgués, Octavio, Sabbaghi, MohammadA, González-Navarrete, Irene, Cristobal, Ion, Serrano, Laia, Zazo, Sandra, Madoz, Juan, Servitja, Sonia, Tusquets, Ignasi, Albanell, Joan, Lluch, Ana, Rovira, Ana, Eroles, Pilar
Publicado no Br J Cancer (2016)

Pan-Cancer Network Analysis Identifies Combinations of Rare Somatic Mutations across Pathways and Protein Complexes

Por Leiserson, Mark D.M., Vandin, Fabio, Wu, Hsin-Ta, Dobson, Jason R., Eldridge, Jonathan V., Thomas, Jacob L., Papoutsaki, Alexandra, Kim, Younhun, Niu, Beifang, McLellan, Michael, Lawrence, Michael S., Gonzalez-Perez, Abel, Tamborero, David, Cheng, Yuwei, Ryslik, Gregory A., Lopez-Bigas, Nuria, Getz, Gad, Ding, Li, Raphael, Benjamin J.
Publicado no Nat Genet (2014)

Pathway and Network Analysis of Cancer Genomes

Por Creixell, Pau, Reimand, Jüri, Haider, Syed, Wu, Guanming, Shibata, Tatsuhiro, Vazquez, Miguel, Mustonen, Ville, Gonzalez-Perez, Abel, Pearson, John, Sander, Chris, Raphael, Benjamin J., Marks, Debora S., Ouellette, B.F. Francis, Valencia, Alfonso, Bader, Gary D., Boutros, Paul C., Stuart, Joshua M., Linding, Rune, Lopez-Bigas, Nuria, Stein, Lincoln D.
Publicado no Nat Methods (2015)